ALS2 / Alsin

amyotrophic lateral sclerosis 2 (juvenile)

ALS2 / Alsin contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.

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Products

Antibodies (27)

Proteins (2)

Type

Primary (27)

Recombinant (2)

Target

ALS2 / Alsin (29)

Reactivity

Human (26)

Mouse (8)

Rat (7)

Bat (4)

Bovine (4)

Chicken (3)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Guinea pig (3)

Horse (4)

Monkey (4)

Rabbit (1)

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Application

IHC (7)

IHC-P (3)

WB (25)

ELISA (10)

ICC (1)

IF (2)

Peptide-ELISA (2)

Host

rabbit (20)

mouse (6)

goat (1)

Product Group

IHCPlus (1)

Isotype

IgG (12)

IgG1,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (21)

Format

APC Conjugated (2)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (14)

Epitope

aa1007-1056 (4)

N-Terminus (1)

aa1-280 (1)

aa1248-1277 (1)

aa1250-1300 (1)

aa1644-1657 (1)

aa177-414 (1)

aa221-321 (1)

Publications

No (29)

Tag

GST, N-terminus (1)

His, N-Terminal (1)

Species

Human (2)

Source

E. coli (1)

Wheat Germ Extract (1)

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IHC-plus™ ALS2 / Alsin Antibody (aa1644-1657) LS-B2740

(4.0) Rating

Antibody:

ALS2 / Alsin Goat anti-Human Polyclonal (aa1644-1657) Antibody

Reactivity:

Rabbit, Dog, Bovine, Rat, Horse, Bat, Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µg/$485

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ALS2 / Alsin Antibody LS-C346241

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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ALS2 / Alsin Antibody LS-C668556

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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ALS2 / Alsin Antibody (aa1-280) LS-C379194

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal (aa1-280) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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ALS2 / Alsin Antibody LS-C659938

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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ALS2 / Alsin Antibody (aa177-414) LS-C178614

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal (aa177-414) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$332

Select

ALS2 / Alsin Antibody (aa1248-1277) LS-C99217

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal (aa1248-1277) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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ALS2 / Alsin Antibody (aa221-321) LS-C306217

Antibody:

ALS2 / Alsin Mouse anti-Human Monoclonal (aa221-321) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

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ALS2 / Alsin Antibody (HRP) LS-C540848

Antibody:

ALS2 / Alsin Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

Select

ALS2 / Alsin Antibody (Biotin) LS-C520715

Antibody:

ALS2 / Alsin Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

ALS2 / Alsin Antibody (FITC) LS-C530759

Antibody:

ALS2 / Alsin Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

ALS2 / Alsin Antibody (APC) LS-C512500

Antibody:

ALS2 / Alsin Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

Select

ALS2 / Alsin Antibody (PE) LS-C648960

Antibody:

ALS2 / Alsin Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

ALS2 / Alsin Antibody LS-C779154

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

ALS2 / Alsin Antibody (N-Terminus) LS-C93909

Antibody:

ALS2 / Alsin Rabbit anti-Rat Polyclonal (N-Terminus) Antibody

Reactivity:

Rat

Applications:

IHC, WB

Format:

Unconjugated

Price:

500 µg/$393

Select

ALS2 / Alsin Antibody LS-C807725

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

ALS2 / Alsin Antibody LS-C309434

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$749

Select

ALS2 / Alsin Antibody (HRP) LS-C540847

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$937

Select

ALS2 / Alsin Antibody (Biotin) LS-C520714

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$937

Select

ALS2 / Alsin Antibody (FITC) LS-C530758

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$937

Select

ALS2 / Alsin Antibody (APC) LS-C512499

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$937

Select

ALS2 / Alsin Antibody (PE) LS-C648958

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$937

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

ALS2 / Alsin Antibody (aa1007-1056) LS-C110908

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal (aa1007-1056) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

ALS2 / Alsin Antibody (aa1007-1056, Biotin) LS-C463530

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal (aa1007-1056) (Biotin) Antibody

Reactivity:

Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Horse, Bat, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

ALS2 / Alsin Antibody (aa1250-1300) LS-C762034

Antibody:

ALS2 / Alsin Rabbit anti-Human Polyclonal (aa1250-1300) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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