Alpha SNAP

N-ethylmaleimide-sensitive factor attachment protein, alpha

The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37%, 60%, and 67% identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively. Platelets contain some of the same proteins, including NSF, p115/TAP, alpha-SNAP, gamma-SNAP, and the t-SNAREs syntaxin-2 and syntaxin-4, that are used in many vesicular transport processes in other cell types. Platelet exocytosis uses a molecular mechanism similar to that used by other secretory cells, such as neurons, although the proteins used by the platelet and their modes of regulation may be quite different.

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Products

Antibodies (27)

Proteins (8)

Type

Over-Expression Lysate (2)

Primary (27)

Recombinant (6)

Target

Alpha SNAP (35)

Reactivity

Human (24)

Mouse (8)

Rat (10)

Bovine (5)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (3)

Horse (3)

Monkey (1)

Pig (3)

Rabbit (3)

Zebrafish (3)

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Application

IHC (8)

IHC-P (2)

WB (24)

ELISA (11)

ICC (2)

IF (1)

IP (3)

Host

rabbit (25)

mouse (2)

Product Group

IHCPlus (1)

Isotype

IgG (15)

IgG1 (2)

Clonality

monoclonal mc (2)

polyclonal pc (25)

Clone

15D4 (1)

Format

AP Conjugated (1)

APC (1)

APC Conjugated (1)

Biotin Conjugated (3)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Preservative Free (1)

Unconjugated (13)

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Epitope

aa1-295 (8)

N-Terminus (4)

aa78-295 (1)

Publications

No (35)

Tag

6His, N-terminus (2)

GST (1)

His (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

Select

Alpha SNAP Antibody (clone 15D4) LS-C26578

Antibody:

Alpha SNAP Mouse anti-Human Monoclonal (15D4) Antibody

Reactivity:

Bovine, Rat

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$466

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IHC-plus™ Alpha SNAP Antibody (aa78-295) LS-B10830

(4.0) Rating

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (aa78-295) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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Alpha SNAP Antibody LS-C376191

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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Alpha SNAP Antibody (HRP) LS-C376189

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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Alpha SNAP Antibody (Biotin) LS-C376193

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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Alpha SNAP Antibody (FITC) LS-C376190

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

Alpha SNAP Antibody (Preservative Free) LS-C818304

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IP, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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Alpha SNAP Antibody LS-C401034

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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Alpha SNAP Antibody (AP) LS-C409494

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (AP) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

AP Conjugated

Price:

20 µl/$275; 100 µl/$389

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Alpha SNAP Antibody LS-C768413

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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Alpha SNAP Antibody LS-C26577

Antibody:

Alpha SNAP Mouse anti-Bovine Monoclonal Antibody

Reactivity:

Bovine, Rat

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$419

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Alpha SNAP Antibody LS-C484823

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

Alpha SNAP Antibody LS-C659585

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$331

Select

Alpha SNAP Antibody LS-C659584

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$331

Select

Alpha SNAP Antibody (N-Terminus) LS-C30717

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

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Alpha SNAP Antibody (N-Terminus, HRP) LS-C481575

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Gibbon, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

Alpha SNAP Antibody (N-Terminus, Biotin) LS-C481573

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Gibbon, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

Alpha SNAP Antibody (N-Terminus, FITC) LS-C481574

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Gibbon, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

Alpha SNAP Antibody (aa1-295) LS-C374611

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (aa1-295) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561

Select

Alpha SNAP Antibody (aa1-295, HRP) LS-C711778

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (aa1-295) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702

Select

Alpha SNAP Antibody (aa1-295, Biotin) LS-C687343

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (aa1-295) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596

Select

Alpha SNAP Antibody (aa1-295, FITC) LS-C694159

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (aa1-295) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755

Select

Alpha SNAP Antibody (aa1-295, Cy3) LS-C702751

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (aa1-295) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008

Select

Alpha SNAP Antibody (aa1-295, PE) LS-C725839

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal (aa1-295) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008

• Unconjugated
• HRP
• Biotin
• FITC
• Cy3
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • Cy3
  • PE

Select

Alpha SNAP Antibody LS-C482928

Antibody:

Alpha SNAP Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321; 200 µl/$386

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