ALOX5AP / FLAP

arachidonate 5-lipoxygenase-activating protein

ALOX5AP / FLAP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

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Products

Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

ALOX5AP / FLAP (6)

Publications

No (6)

Tag

6His-SUMO, N-terminus (1)

GST (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

Baculovirus (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (1)

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Human ALOX5AP / FLAP Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64766

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18 kDa

Price:

20 µg/$1,107

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ALOX5AP / FLAP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99495

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18 kDa

Price:

100 µg/$494

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Human ALOX5AP / FLAP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74146

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18 kDa

Price:

20 µg/$150

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Human ALOX5AP / FLAP Protein (Recombinant 6His-SUMO, N-terminus) (Full Length) - LS-G136893

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Molecular Weight:

34.2 kDa

Price:

100 µg/$1,801; 20 µg/$1,247

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Human ALOX5AP / FLAP Protein (Recombinant GST) (Full Length) - LS-G27429

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

43.45 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ALOX5AP / FLAP Protein (Recombinant His) (Met1-Pro161) - LS-G97153

Source:

Baculovirus

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

19 kDa

Price:

100 µg/$1,047

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