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ALOX5AP / FLAP

arachidonate 5-lipoxygenase-activating protein

ALOX5AP / FLAP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene Name: arachidonate 5-lipoxygenase-activating protein
Synonyms: ALOX5AP, FLAP, MK-886-binding protein
Target Sequences: NM_001629 NP_001620.2 P20292

☰ Filters
Antibodies (8)
Proteins (6)
ELISA Kits (2)
Over-Expression Lysate (2)
Primary (8)
Recombinant (4)
Sandwich (2)
ALOX5AP / FLAP (16)
Human (8)
Rat (3)
Monkey (1)
IHC (4)
IHC-P (3)
WB (7)
ELISA (1)
Peptide-ELISA (4)
rabbit (5)
goat (3)
Product Group
IHCPlus (2)
IgG (1)
polyclonal pc (8)
96-Well Microplate (1)
96-Well Strip Plate (1)
Biotin Conjugated (1)
Unconjugated (7)
Internal Region (1)
aa148-161 (1)
aa28-40 (1)
aa86-117 (1)
No (16)
Plasma (2)
Serum (2)
Tissue Homogenates (1)
6His-SUMO, N-terminus (1)
GST (1)
His (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
Baculovirus (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (1)
ALOX5AP / FLAP Antibody - Anti-ALOX5AP / FLAP antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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ALOX5AP / FLAP Goat anti-Human Polyclonal (aa28-40) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
ALOX5AP / FLAP Antibody - Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ALOX5AP antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ALOX5AP / FLAP Rabbit anti-Human Polyclonal (aa86-117) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
ALOX5AP / FLAP Antibody - Anti-ALOX5AP / FLAP antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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ALOX5AP / FLAP Goat anti-Human Polyclonal (aa148-161) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
ALOX5AP / FLAP Antibody - Biotinylated antibody (0.3µg/ml) staining of U937 lysate (35µg protein in RIPA buffer), exactly mirroring its parental non-biotinylated product. Primary incubation was 1 hour. Detected by chemiluminescence, using streptavidin-HRP and using NAP blocker as a
Select
ALOX5AP / FLAP Goat anti-Human Polyclonal (Internal Region) (Biotin) Antibody
Human
IHC, Peptide-ELISA, WB
Biotin Conjugated
100 µg/$503
ALOX5AP / FLAP Antibody - Western blot analysis of ALOX5AP using HepG2 whole cells lysates
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ALOX5AP / FLAP Rabbit anti-Human Polyclonal Antibody
Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
ALOX5AP / FLAP Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
ALOX5AP / FLAP Antibody - Western blot of FLAP antibody on human kidney cell lysate. Lysate used at 15 ug/lane. Antibody used at 5 ug/ml. Secondary antibody, mouse anti-rabbit HRP, used at 1:25k dilution. Visualized using Pierce West Femto substrate system. Exposure for 5 minutes
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ALOX5AP / FLAP Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$466
ALOX5AP / FLAP Antibody - Western blot of antigen immunoaffinity purified and FLAP antibody on human kidney cell lysate. Lysate used at 15 ug/lane. Antibody used at 5 ug/ml. Secondary antibody, mouse anti-rabbit HRP, used at 1:75k dilution. Visualized using Pierce West Femto substrate system. Exposure for 5 minutes
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ALOX5AP / FLAP Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$466
ALOX5AP / FLAP ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ALOX5AP / FLAP Protein - Purified recombinant protein ALOX5AP was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
18 kDa
20 µg/$1,107
ALOX5AP / FLAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
18 kDa
100 µg/$494
ALOX5AP / FLAP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
18 kDa
20 µg/$150
ALOX5AP / FLAP Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
34.2 kDa
100 µg/$1,801; 20 µg/$1,247
ALOX5AP / FLAP ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
ALOX5AP / FLAP Protein - 12.5% SDS-PAGE of human ALOX5AP stained with Coomassie Blue
Select
Wheat Germ Extract
GST
43.45 kDa
10 µg/$479; 25 µg/$670
Select
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
19 kDa
100 µg/$1,047
Viewing 1-16 of 16 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).