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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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ALOX12B

Arachidonate 12-lipoxygenase, 12R Type

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12R)-hydroperoxyeicosatetraenoic acid/(12R)-HPETE and minor stereoisomers. In the skin, acts upstream of ALOXE3 on the lineolate moiety of esterified omega-hydroxyacyl-sphingosine (EOS) ceramides to produce an epoxy-ketone derivative, a crucial step in the conjugation of omega-hydroxyceramide to membrane proteins. Therefore plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. May also play a role in the regulation of the expression of airway mucins.

Gene Name: Arachidonate 12-lipoxygenase, 12R Type
Family/Subfamily: Lipoxygenase
Synonyms: ALOX12B, 12R-LOX, 12R-lipoxygenase, Epidermis-type lipoxygenase 12
Target Sequences: NM_001139 NP_001130.1 O75342

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Products
Antibodies (24)
Primary (24)
ALOX12B (24)
Human (16)
Mouse (8)
IHC (7)
IHC-P (1)
WB (23)
Flo (7)
ELISA (7)
rabbit (23)
mouse (1)
IgG (6)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (23)
3G12 (1)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (3)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (5)
aa622-652 (7)
No (24)
ALOX12B Antibody - Western Blot; Sample: Recombinant ALOX12B, Mouse.
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ALOX12B Rabbit anti-Mouse Polyclonal Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
ALOX12B Antibody - Western Blot; Sample: Recombinant ALOX12B, Mouse.
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ALOX12B Rabbit anti-Mouse Polyclonal (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
ALOX12B Antibody - Western Blot; Sample: Recombinant ALOX12B, Mouse.
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ALOX12B Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
ALOX12B Antibody - Western Blot; Sample: Recombinant ALOX12B, Mouse.
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ALOX12B Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
ALOX12B Antibody - Western Blot; Sample: Recombinant ALOX12B, Mouse.
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ALOX12B Rabbit anti-Mouse Polyclonal (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
ALOX12B Antibody - Western Blot; Sample: Recombinant ALOX12B, Mouse.
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ALOX12B Rabbit anti-Mouse Polyclonal (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
ALOX12B Antibody - Western Blot; Sample: Recombinant ALOX12B, Mouse.
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ALOX12B Rabbit anti-Mouse Polyclonal (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
ALOX12B Antibody - Western Blot; Sample: Recombinant ALOX12B, Mouse.
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ALOX12B Rabbit anti-Mouse Polyclonal (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
ALOX12B Antibody - ALOX12B antibody immunohistochemistry of formalin-fixed and paraffin-embedded human tonsil tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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ALOX12B Rabbit anti-Human Polyclonal (aa622-652) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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ALOX12B Rabbit anti-Human Polyclonal (aa622-652) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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ALOX12B Rabbit anti-Human Polyclonal (aa622-652) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
Select
ALOX12B Rabbit anti-Human Polyclonal (aa622-652) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
Select
ALOX12B Rabbit anti-Human Polyclonal (aa622-652) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
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ALOX12B Rabbit anti-Human Polyclonal (aa622-652) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
Select
ALOX12B Rabbit anti-Human Polyclonal (aa622-652) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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ALOX12B Mouse anti-Human Monoclonal (3G12) Antibody
Human
ELISA
Unconjugated
100 µg/$423
ALOX12B Antibody - Western Blot; Sample: Recombinant protein.
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ALOX12B Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
ALOX12B Antibody - Western Blot; Sample: Recombinant protein.
Select
ALOX12B Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
ALOX12B Antibody - Western Blot; Sample: Recombinant protein.
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ALOX12B Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
ALOX12B Antibody - Western Blot; Sample: Recombinant protein.
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ALOX12B Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
ALOX12B Antibody - Western Blot; Sample: Recombinant protein.
Select
ALOX12B Rabbit anti-Human Polyclonal (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
ALOX12B Antibody - Western Blot; Sample: Recombinant protein.
Select
ALOX12B Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
ALOX12B Antibody - Western Blot; Sample: Recombinant protein.
Select
ALOX12B Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
ALOX12B Antibody - Western Blot; Sample: Recombinant protein.
Select
ALOX12B Rabbit anti-Human Polyclonal (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).