ALOX12B

Arachidonate 12-lipoxygenase, 12R Type

Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12R)-hydroperoxyeicosatetraenoic acid/(12R)-HPETE and minor stereoisomers. In the skin, acts upstream of ALOXE3 on the lineolate moiety of esterified omega-hydroxyacyl-sphingosine (EOS) ceramides to produce an epoxy-ketone derivative, a crucial step in the conjugation of omega-hydroxyceramide to membrane proteins. Therefore plays a crucial role in the synthesis of corneocytes lipid envelope and the establishment of the skin barrier to water loss. May also play a role in the regulation of the expression of airway mucins.

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Products

Antibodies (24)

Proteins (6)

Type

Over-Expression Lysate (2)

Primary (24)

Recombinant (4)

Target

ALOX12B (30)

Reactivity

Human (16)

Mouse (8)

Application

IHC (7)

IHC-P (1)

WB (23)

Flo (7)

ELISA (7)

Host

rabbit (23)

mouse (1)

Isotype

IgG (6)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (23)

Clone

3G12 (1)

Format

APC (2)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (3)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (3)

Unconjugated (5)

Epitope

aa622-652 (7)

Publications

No (30)

Tag

GST (1)

GST, N-terminus (1)

His-T7, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Mouse (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (3)

Select

ALOX12B Antibody LS-C663303

Antibody:

ALOX12B Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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ALOX12B Antibody (HRP) LS-C712221

Antibody:

ALOX12B Rabbit anti-Mouse Polyclonal (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

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ALOX12B Antibody (Biotin) LS-C687679

Antibody:

ALOX12B Rabbit anti-Mouse Polyclonal (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

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ALOX12B Antibody (FITC) LS-C694538

Antibody:

ALOX12B Rabbit anti-Mouse Polyclonal (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

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ALOX12B Antibody (Cy3) LS-C703197

Antibody:

ALOX12B Rabbit anti-Mouse Polyclonal (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

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ALOX12B Antibody (PE) LS-C726281

Antibody:

ALOX12B Rabbit anti-Mouse Polyclonal (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

ALOX12B Antibody (APC) LS-C740903

Antibody:

ALOX12B Rabbit anti-Mouse Polyclonal (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

ALOX12B Antibody (APC, Cy7) LS-C735217

Antibody:

ALOX12B Rabbit anti-Mouse Polyclonal (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781

• Unconjugated
• HRP
• Biotin
• FITC
• Cy3
• PE
• APC
• More...
  • APC, Cy7

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • Cy3
  • PE
  • APC
  • APC, Cy7

Select

ALOX12B Antibody (aa622-652) LS-C156289

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (aa622-652) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

ALOX12B Antibody (aa622-652) LS-C319437

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (aa622-652) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

ALOX12B Antibody (aa622-652, Biotin) LS-C212705

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (aa622-652) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

ALOX12B Antibody (aa622-652, FITC) LS-C212706

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (aa622-652) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

ALOX12B Antibody (aa622-652, PE) LS-C212708

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (aa622-652) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

ALOX12B Antibody (aa622-652, APC) LS-C212704

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (aa622-652) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

ALOX12B Antibody (aa622-652, Azide-free, HRP) LS-C212707

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (aa622-652) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• APC
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • APC
  • HRP, Azide-free

Select

Human ALOX12B Protein (Recombinant His-T7, N-terminus) (Leu479-Ile701) - LS-G133294

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

29.6kDa

Price:

10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

Select

ALOX12B Antibody (clone 3G12) LS-C196647

Antibody:

ALOX12B Mouse anti-Human Monoclonal (3G12) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$423

Select

ALOX12B Antibody LS-C663305

Antibody:

ALOX12B Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

Select

ALOX12B Antibody (HRP) LS-C712220

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593

Select

ALOX12B Antibody (Biotin) LS-C687681

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

Select

ALOX12B Antibody (FITC) LS-C694533

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

Select

ALOX12B Antibody (Cy3) LS-C703196

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

Select

ALOX12B Antibody (PE) LS-C726278

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

Select

ALOX12B Antibody (APC) LS-C740906

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

Select

ALOX12B Antibody (APC, Cy7) LS-C735214

Antibody:

ALOX12B Rabbit anti-Human Polyclonal (APC, Cy7) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676

• Unconjugated
• HRP
• Biotin
• FITC
• Cy3
• PE
• APC
• More...
  • APC, Cy7

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • Cy3
  • PE
  • APC
  • APC, Cy7

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