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ALKBH4
AlkB, Alkylation Repair Homolog 4 (E. Coli)
Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation.
| Gene Name: | AlkB, Alkylation Repair Homolog 4 (E. Coli) |
| Synonyms: | ALKBH4, ABH4 |
| Target Sequences: | NM_017621 NP_060091.1 Q9NXW9 |
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