ALK-6 / BMPR1B

bone morphogenetic protein receptor, type IB

ALK-6 / BMPR1B is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene.

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ELISA Kits (1)

Type

Sandwich (1)

Target

ALK-6 / BMPR1B (1)

Reactivity

Human (1)

Format

96-Well Strip Plate (1)

Publications

No (1)

Sample Type

Tissue Homogenates (1)

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Human ALK-6 / BMPR1B (Sandwich ELISA) ELISA Kit - LS-F7275

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$764

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