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ALG10 / KCR1 is a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go (EAG) potassium ion channel.
Gene Name: | ALG10, alpha-1,2-glucosyltransferase |
Synonyms: | ALG10, Alpha2-glucosyltransferase, ALG10A, DIE2, Potassium channel regulator 1, KCR1 |
Target Sequences: | NM_032834 NP_116223.3 Q5BKT4 |
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