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ALDOC / Aldolase 3 encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.
Gene Name: | aldolase C, fructose-bisphosphate |
Synonyms: | ALDOC, ALDC, Aldolase 3, Fructoaldolase C, Brain-type aldolase |
Target Sequences: | NM_005165 NP_005156.1 P09972 |
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