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ALDOA / Aldolase A
aldolase A, fructose-bisphosphate
ALDOA / Aldolase A, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.
| Gene Name: | aldolase A, fructose-bisphosphate |
| Synonyms: | ALDOA, ALDA, Aldolase, GSD12, Muscle-type aldolase, Lung cancer antigen NY-LU-1 |
| Target Sequences: | NM_000034 NP_000025.1 P04075 |
Publications (2)
1
The deubiquitinase JOSD2 is a positive regulator of glucose metabolism. Lyudmila Krassikova , Boxi Zhang , Divya Nagarajan, André Lima Queiroz, Merve Kacal, Evangelos Samakidis, Helin Vakifahmetoglu-Norberg, Erik Norberg. Cell death and differentiation. 2020 October; [Full Text Article]
[PubMed:33082514]
[PMC:PMC7937685]
Related Antibodies: LS-B1461.
2
Proteomic profiling of osteosarcoma cells identifies ALDOA and SULT1A3 as negative survival markers of human osteosarcoma. Chen X, Yang TT, Zhou Y, Wang W, Qiu XC, Gao J, Li CX, Long H, Ma BA, Ma Q, Zhang XZ, Yang LJ, Fan QY. Molecular carcinogenesis. 2014 Feb;53:138-44. [Full Text Article]
[PubMed:22949271]
Related Antibodies: LS-B1461.
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ALDOA / Aldolase A
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ALDOA / Aldolase A Goat anti-Rabbit Polyclonal (Lyophilized) Antibody
Rabbit, Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated, Lyophilized
500 µg/$485
ALDOA / Aldolase A Mouse anti-Human Monoclonal (2E6) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ALDOA / Aldolase A Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Mouse, Dog, Rat, Human
ICC, IF, IP, WB
Unconjugated
100 µl/$299
ALDOA / Aldolase A Rabbit anti-Human Polyclonal (aa66-95) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
ALDOA / Aldolase A Sheep anti-Rabbit Polyclonal Antibody
Rabbit
ELISA, IF, IHC, WB
Unconjugated
10 mg/$335
ALDOA / Aldolase A Rabbit anti-Human Polyclonal (aa303-331) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
ALDOA / Aldolase A Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
ALDOA / Aldolase A Rabbit anti-Human Polyclonal (Thr9) Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$321; 100 µl/$403
ALDOA / Aldolase A Goat anti-Rabbit Polyclonal (HRP) Antibody
Rabbit, Human
ELISA, IHC, WB
HRP Conjugated
100 µg/$896
ALDOA / Aldolase A Rabbit anti-Rat Polyclonal Antibody
Rat
ICC, IP, WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
ALDOA / Aldolase A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$331
ALDOA / Aldolase A Mouse anti-Human Monoclonal (1C5B2) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
ALDOA / Aldolase A Mouse anti-Human Monoclonal (2H2B1) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
100 µl/$459
ALDOA / Aldolase A Mouse anti-Human Monoclonal (AT3F9) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
ALDOA / Aldolase A Sheep anti-Rabbit Polyclonal Antibody
Rabbit
ELISA, IF, IHC, WB
Unconjugated
1 mg/$520
ALDOA / Aldolase A Goat anti-Rabbit Polyclonal (Biotin) Antibody
Rabbit
ELISA, IF, IHC, WB
Biotin Conjugated
100 µg/$896
ALDOA / Aldolase A Sheep anti-Rabbit Polyclonal (Biotin) Antibody
Rabbit
ELISA, IF, IHC, WB
Biotin Conjugated
1 ml/$438
ALDOA / Aldolase A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
ALDOA / Aldolase A Mouse anti-Human Monoclonal (3D9-6F3) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$705
ALDOA / Aldolase A Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IF, WB
Biotin Conjugated
100 µl/$904
ALDOA / Aldolase A Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IF, WB
FITC Conjugated
100 µl/$904
ALDOA / Aldolase A Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IF, WB
APC Conjugated
100 µl/$904
ALDOA / Aldolase A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ALDOA / Aldolase A Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ALDOA / Aldolase A Rabbit anti-Human Polyclonal (1-80 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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