ALDH2

aldehyde dehydrogenase 2 family (mitochondrial)

This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Products

Antibodies (65)

ELISA Kits (13)

Proteins (9)

Type

Custom (3)

Over-Expression Lysate (2)

Primary (65)

Recombinant (7)

Sandwich (9)

Sandwich CLIA (1)

Target

ALDH2 (87)

Reactivity

Human (68)

Mouse (28)

Rat (17)

Hamster (1)

Monkey (4)

Non-Human Primate (1)

Pig (1)

Rabbit (1)

Application

IHC (32)

IHC-P (9)

WB (62)

Flo (13)

ELISA (29)

ICC (8)

IF (15)

IP (1)

Peptide-ELISA (2)

Host

rabbit (47)

mouse (16)

goat (2)

Product Group

IHCPlus (4)

Isotype

IgG (28)

IgG1 (5)

IgG1,k (6)

IgG2a,k (2)

IgG3 (2)

Clonality

monoclonal mc (17)

polyclonal pc (48)

Clone

138CT22.3.8 (6)

1E5 (1)

4G6A3 (3)

AT2C10 (1)

EPR4493 (1)

OTI4H2 (2)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (11)

APC (1)

APC Conjugated (5)

Azide-free (3)

Biotin Conjugated (7)

Carrier-free (1)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (5)

Unconjugated (34)

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Epitope

aa59-150 (8)

aa318-347 (7)

aa52-81 (7)

aa401-450 (4)

aa317-517 (2)

41-90 aa, N-terminal (1)

Amino Acid: 317-517 (1)

Internal (1)

Internal Region (1)

N-Terminus (1)

aa18-33 (1)

aa18-48 (1)

aa363-375 (1)

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Publications

No (86)

Yes (1)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (8)

Serum (8)

Tissue Homogenates (6)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His-S (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (1)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (1)

Biologically Active

Biologically active (1)

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IHC-plus™ ALDH2 Antibody (aa52-81) LS-B3390

(4.0) Rating

Antibody:

ALDH2 Rabbit anti-Human Polyclonal (aa52-81) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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IHC-plus™ ALDH2 Antibody (aa318-347) LS-B7924

(5.0) Rating

(1) Publication(s)

Antibody:

ALDH2 Rabbit anti-Human Polyclonal (aa318-347) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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ALDH2 Antibody LS-C156258

Antibody:

ALDH2 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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Human ALDH2 (Sandwich ELISA) ELISA Kit - LS-F5833

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Human ALDH2 Protein (Recombinant) - LS-G486

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$317; 500 µg/$526; 20 µg/$245

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IHC-plus™ ALDH2 Antibody (Internal, clone EPR4493) LS-B7921

(4.0) Rating

Antibody:

ALDH2 Rabbit anti-Human Monoclonal (Internal) (EPR4493) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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Mouse ALDH2 (Sandwich ELISA) ELISA Kit - LS-F19070

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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IHC-plus™ ALDH2 Antibody (41-90 aa, N-terminal) LS-B15550

(4.0) Rating

Antibody:

ALDH2 Rabbit anti-Human Polyclonal (41-90 aa, N-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

ALDH2 Antibody (aa317-517, clone 4G6A3) LS-C191809

Antibody:

ALDH2 Mouse anti-Human Monoclonal (aa317-517) (4G6A3) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

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Mouse ALDH2 Protein (Recombinant His) - LS-G3318

Source:

E. coli

Tag:

His

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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ALDH2 Antibody (aa18-33) LS-C313509

Antibody:

ALDH2 Rabbit anti-Human Polyclonal (aa18-33) Antibody

Reactivity:

Rabbit, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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ALDH2 Antibody (aa18-48) LS-C407685

Antibody:

ALDH2 Rabbit anti-Human Polyclonal (aa18-48) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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ALDH2 Antibody (Amino Acid: 317-517, clone 4G6A3) LS-C759213

Antibody:

ALDH2 Mouse anti-Human Monoclonal (Amino Acid: 317-517) (4G6A3) Antibody

Reactivity:

Mouse, Rat, Non-Human Primate, Human

Applications:

Flo, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$503

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ALDH2 Antibody (aa317-517, clone 4G6A3) LS-C191808

Antibody:

ALDH2 Mouse anti-Human Monoclonal (aa317-517) (4G6A3) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

ALDH2 Antibody (clone 138CT22.3.8) LS-C319108

Antibody:

ALDH2 Mouse anti-Human Monoclonal (138CT22.3.8) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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ALDH2 Antibody (clone 138CT22.3.8, Biotin) LS-C250116

Antibody:

ALDH2 Mouse anti-Human Monoclonal (Biotin) (138CT22.3.8) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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ALDH2 Antibody (clone 138CT22.3.8, FITC) LS-C250117

Antibody:

ALDH2 Mouse anti-Human Monoclonal (FITC) (138CT22.3.8) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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ALDH2 Antibody (clone 138CT22.3.8, APC) LS-C250115

Antibody:

ALDH2 Mouse anti-Human Monoclonal (APC) (138CT22.3.8) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

ALDH2 Antibody (clone 138CT22.3.8, Azide-free, HRP) LS-C250118

Antibody:

ALDH2 Mouse anti-Human Monoclonal (Azide-free) (HRP) (138CT22.3.8) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

ALDH2 Antibody (clone 138CT22.3.8, PE) LS-C250120

Antibody:

ALDH2 Mouse anti-Human Monoclonal (PE) (138CT22.3.8) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

ALDH2 Antibody LS-C659346

Antibody:

ALDH2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

ALDH2 Antibody LS-C331368

Antibody:

ALDH2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

Human ALDH2 (Sandwich ELISA) ELISA Kit - LS-F21919

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Human ALDH2 (CLIA) ELISA Kit - LS-F29288

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

78.13 - 5000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

ALDH2 Antibody (clone OTI4H2) LS-C114711

Antibody:

ALDH2 Mouse anti-Human Monoclonal (OTI4H2) Antibody

Reactivity:

Human

Applications:

Flo, IF

Format:

Unconjugated

Price:

100 µl/$434

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