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ALDH1A3

aldehyde dehydrogenase 1 family, member A3

Aldehyde dehydrogenase (ALDH) isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene for the human isozyme ALDH6 spans about 37 kb and consists of 13 exons. It is expressed at low levels in many tissues and at higher levels in salivary gland, stomach and kidney. The major transcript is approximately 3.5 kb however there is a less abundant transcript that is smaller by 111 bp in the 3' non-coding region and uses an alternative polyadenylation signal. The significance of alternative splicing of ALDH6 gene is currently unclear.

Gene Name: aldehyde dehydrogenase 1 family, member A3
Synonyms: ALDH1A3, Acetaldehyde dehydrogenase 6, ALDH6, Aldehyde dehydrogenase 6, ALDH1A6, RALDH3, Retinaldehyde dehydrogenase 3, RALDH-3
Target Sequences: NM_000693 NP_000684.2 P47895

Publications (1)

1
Heterogeneity of Human Breast Stem and Progenitor Cells as Revealed by Transcriptional Profiling. Colacino JA, Azizi E, Brooks MD, Harouaka R, Fouladdel S, McDermott SP, Lee M, Hill D, Madden J, Boerner J, Cote ML, Sartor MA, Rozek LS, Wicha MS. Stem cell reports. 2018 May;10:1596-1609. (Human) [Full Text Article] [PubMed:29606612] [PMC:PMC5995162] Related Antibodies: LS-C172937.

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Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
ALDH1A3 (8)
No (8)
6His, N-terminus (2)
6His-SUMO, N-terminus (1)
GST, N-terminus + His, C-terminus (1)
His (1)
His,N-terminus (1)
Myc-DDK (Flag) (2)
Human (7)
293T Cells (1)
E. coli (5)
HEK 293 Cells (1)
Yeast (1)
Purified (2)
Low endotoxin level (2)
ALDH1A3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
55.9 kDa
100 µg/$494
ALDH1A3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
55.9 kDa
20 µg/$150
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E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
57.5kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
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E. coli
His,N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
57.5 kDa
10 µg/$368; 50 µg/$479
ALDH1A3 Protein
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E. coli
GST, N-terminus + His, C-terminus
83.9 kDa
50 µg/$419
ALDH1A3 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-SUMO, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
ALDH1A3 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
ALDH1A3 Protein - Recombinant Aldehyde Dehydrogenase 1 Family, Member A3 By SDS-PAGE
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E. coli
His
21.2 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).