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ALDH1A1 / ALDH1

aldehyde dehydrogenase 1 family, member A1

ALDH1A1 / ALDH1 belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet.

Gene Name: aldehyde dehydrogenase 1 family, member A1
Synonyms: ALDH1A1, Acetaldehyde dehydrogenase 1, ALDH class 1, ALDC, Aldehyde dehydrogenase 1, ALDH-E1, ALDH1, ALDH11, PUMB1, RALDH 1, RALDH1, ALHDII, Retinal dehydrogenase 1, Retinaldehyde dehydrogenase 1
Target Sequences: NM_000689 NP_000680.2 P00352

Publications (3)

1
Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling. Ming Luo, Li Shang, Michael D Brooks, Evelyn Jiagge, Yongyou Zhu, Johanna M Buschhaus, Sarah Conley, Melissa A Fath, April Davis, Elizabeth Gheordunescu, Yongfang Wang, Ramdane Harouaka, Ann Lozier, Daniel Triner, Sean McDermott, Sofia D Merajver, Gary D Luker, Douglas R Spitz, Max S Wicha. Cell metabolism. 2018 July;28:69-86.e6. [Full Text Article] [PubMed:29972798] [PMC:PMC6037414]
2
BRCA1 mutation influences progesterone response in human benign mammary organoids. Batzaya Davaadelger, Mi-Ran Choi, Hari Singhal, Susan E Clare, Seema A Khan, J Julie Kim. Breast cancer research : BCR. 2019 Nov;21:124. [Full Text Article] [PubMed:31771627] [PMC:PMC6878650] Related Antibodies: LS-B10149.
3
Expanding the use of monoclonal antibody therapy of cancer by using ionising radiation to upregulate antibody targets. Wattenberg MM, Kwilas AR, Gameiro SR, Dicker AP, Hodge JW. British journal of cancer. 2014 Mar;110:1472-80. [Full Text Article] [PubMed:24556625] [PMC:PMC3960628] Related Antibodies: LS-B2497.

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ELISA Kits (9)
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ALDH1A1 / ALDH1 (9)
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ALDH1A1 / ALDH1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$748
ALDH1A1 / ALDH1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.56 - 100 U/l
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ALDH1A1 / ALDH1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
ALDH1A1 / ALDH1 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
ALDH1A1 / ALDH1 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
ALDH1A1 / ALDH1 ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
ALDH1A1 / ALDH1 ELISA Kit
Select
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
ALDH1A1 / ALDH1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.56 - 100 mIU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
ALDH1A1 / ALDH1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.4 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$610
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).