ALAS1

aminolevulinate, delta-, synthase 1

ALAS1 encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified.

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Products

Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

ALAS1 (6)

Publications

No (6)

Tag

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (4)

Species

Human (5)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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Human ALAS1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103436

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.4 kDa

Price:

100 µg/$494

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Human ALAS1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88017

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.4 kDa

Price:

20 µg/$150

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Human ALAS1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88018

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.4 kDa

Price:

20 µg/$150

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Human ALAS1 Protein (Recombinant GST, N-terminus) (aa1-98) - LS-G57741

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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ALAS1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99114

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.4 kDa

Price:

100 µg/$494

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Human ALAS1 Protein (Recombinant His, N-Terminal) - LS-G144668

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

70.4 kDa

Price:

50 µg/$419

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