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ALAS1

aminolevulinate, delta-, synthase 1

ALAS1 encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene Name: aminolevulinate, delta-, synthase 1
Synonyms: ALAS1, ALAS, ALAS-H, ALAS3, ALASH, Delta-ALA synthase 1, MIG4, Migration-inducing protein 4
Target Sequences: NM_000688 NP_000679.1 P13196

☰ Filters
Antibodies (24)
Proteins (6)
ELISA Kits (1)
Over-Expression Lysate (4)
Primary (24)
Recombinant (2)
Sandwich (1)
ALAS1 (31)
Human (24)
Mouse (7)
Rat (7)
Bovine (3)
Chimpanzee (6)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (3)
Zebrafish (3)
IHC (6)
IHC-P (6)
WB (19)
ELISA (1)
ICC (1)
IF (5)
Peptide-ELISA (1)
rabbit (19)
mouse (5)
Product Group
IHCPlus (2)
IgG (14)
IgG1 (4)
IgG2a,k (1)
monoclonal mc (5)
polyclonal pc (19)
3G10 (1)
OTI1C5 (2)
OTI5D5 (2)
96-Well Strip Plate (1)
Biotin Conjugated (3)
Carrier-free (2)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (15)
aa146-195 (4)
aa46-95 (4)
aa57-308 (4)
aa1-250 (1)
aa480-530 (1)
No (30)
Yes (1)
Tissue Homogenates (1)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (4)
Human (5)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
ALAS1 Antibody - Anti-ALAS1 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ALAS1 Rabbit anti-Human Polyclonal (aa480-530) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
ALAS1 Antibody - Immunofluorescent analysis of ALAS-H staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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ALAS1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
ALAS1 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALAS1 Rabbit anti-Human Polyclonal (aa146-195) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ALAS1 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALAS1 Rabbit anti-Human Polyclonal (aa146-195) (HRP) Antibody
Zebrafish, Horse, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
ALAS1 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALAS1 Rabbit anti-Human Polyclonal (aa146-195) (Biotin) Antibody
Zebrafish, Horse, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
ALAS1 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALAS1 Rabbit anti-Human Polyclonal (aa146-195) (FITC) Antibody
Zebrafish, Horse, Mouse, Dog, Guinea pig, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
ALAS1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
70.4 kDa
100 µg/$494
ALAS1 Antibody - Immunofluorescence analysis of HeLa cells.
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ALAS1 Rabbit anti-Human Polyclonal (aa1-250) Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ALAS1 Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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ALAS1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ALAS1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
20 µl/$275; 100 µl/$389
ALAS1 Antibody - ALAS1 monoclonal antibody (M01), clone 3G10 Western Blot analysis of ALAS1 expression in JAR.
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ALAS1 Mouse anti-Human Monoclonal (3G10) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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ALAS1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ALAS1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ALAS1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALAS1 (1:2000).
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ALAS1 Mouse anti-Human Monoclonal (aa57-308) (OTI1C5) Antibody
Human
WB
Unconjugated
100 µl/$434
ALAS1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY ALAS1. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALAS1. (1:2000)
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ALAS1 Mouse anti-Human Monoclonal (aa57-308) (Carrier-free) (OTI1C5) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
ALAS1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY ALAS1. (Right lane) cDNA for 48 hrs and lysed
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ALAS1 Mouse anti-Human Monoclonal (aa57-308) (OTI5D5) Antibody
Human
WB
Unconjugated
100 µl/$434
ALAS1 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY ALAS1. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ALAS1. (1:2000)
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ALAS1 Mouse anti-Human Monoclonal (aa57-308) (Carrier-free) (OTI5D5) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
ALAS1 Antibody - ALAS1 antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALAS1 Rabbit anti-Human Polyclonal (aa46-95) Antibody
Human
WB
Unconjugated
100 µl/$424
ALAS1 Antibody - ALAS1 antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALAS1 Rabbit anti-Human Polyclonal (aa46-95) (HRP) Antibody
Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
ALAS1 Antibody - ALAS1 antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALAS1 Rabbit anti-Human Polyclonal (aa46-95) (Biotin) Antibody
Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
ALAS1 Antibody - ALAS1 antibody Western Blot of 293T. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ALAS1 Rabbit anti-Human Polyclonal (aa46-95) (FITC) Antibody
Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
ALAS1 Antibody - Fig-1: Western blot analysis of ALAS1. Anti-ALAS1 antibody was used at 2 µg/ml on (1) h Liver and (2) h Stomach lysates.
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ALAS1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
25 µg/$281; 100 µg/$400
ALAS1 Antibody - Immunohistochemistry image of paraffin-embedded human liver cancer at a dilution of 1:100
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ALAS1 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
ALAS1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
ALAS1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
ALAS1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 31 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).