AKTIP / FTS

AKT interacting protein

The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.

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Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

AKTIP / FTS (7)

Publications

No (7)

Tag

GST (1)

His-SUMO (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human AKTIP / FTS Protein (Recombinant GST) (Full Length) - LS-G34985

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

57.86 kDa

Price:

10 µg/$479; 25 µg/$670

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Human AKTIP / FTS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84640

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.9 kDa

Price:

20 µg/$150

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Human AKTIP / FTS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84641

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.9 kDa

Price:

20 µg/$150

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Human AKTIP / FTS Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69435

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.9 kDa

Price:

20 µg/$1,107

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AKTIP / FTS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121379

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.9 kDa

Price:

100 µg/$494

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AKTIP / FTS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110341

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.9 kDa

Price:

100 µg/$494

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Human AKTIP / FTS Protein (Recombinant His-SUMO) (Full Length) - LS-G21913

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

49.1 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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