AKT3

v-akt murine thymoma viral oncogene homolog 3

AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT3 is the least studied AKT isoform. It plays an important role in brain development and is crucial for the viability of malignant glioma cells. AKT3 isoform may also be the key molecule in up-regulation and down-regulation of MMP13 via IL13. Required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands. Down-regulation by RNA interference reduces the expression of the phosphorylated form of BAD, resulting in the induction of caspase-dependent apoptosis.

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Products

ELISA Kits (7)

Type

Competitive EIA (1)

Sandwich (6)

Target

AKT3 (7)

Reactivity

Human (3)

Mouse (1)

Rat (2)

Monkey (1)

Format

96-Well Strip Plate (7)

Publications

No (7)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (5)

Serum (5)

Tissue Homogenates (2)

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Rat AKT3 (Sandwich ELISA) ELISA Kit - LS-F55992

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$587

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Human AKT3 (Sandwich ELISA) ELISA Kit - LS-F49189

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human AKT3 (Sandwich ELISA) ELISA Kit - LS-F4162

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$764

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Monkey AKT3 (Sandwich ELISA) ELISA Kit - LS-F47350

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Rat AKT3 (Sandwich ELISA) ELISA Kit - LS-F49270

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Mouse AKT3 (Sandwich ELISA) ELISA Kit - LS-F49243

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human AKT3 (Competitive EIA) ELISA Kit - LS-F28824

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

5 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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