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AKR7A2 / AFAR

aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)

Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

Gene Name: aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
Synonyms: AKR7A2, AFB1-AR 1, AKR7, AFB1 aldehyde reductase 1, AFB1-AR1, AFAR, AFAR1, Aldoketoreductase 7, SSA reductase
Target Sequences: NM_003689 NP_003680.2 O43488

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Products
Antibodies (33)
Primary (33)
AKR7A2 / AFAR (33)
Human (33)
Mouse (6)
Rat (7)
Chimpanzee (3)
Gibbon (3)
Orangutan (3)
IHC (11)
IHC-P (4)
WB (32)
ELISA (9)
ICC (2)
IF (4)
IP (1)
Peptide-ELISA (1)
rabbit (26)
mouse (7)
IgG (16)
IgG1,k (6)
monoclonal mc (6)
polyclonal pc (27)
APC Conjugated (2)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (17)
N-Terminus (4)
aa82-131 (4)
aa101-129 (1)
aa84-359 (1)
No (33)
AKR7A2 / AFAR Antibody - Immunohistochemical analysis of AKR7A2 staining in mouse heart formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
AKR7A2 / AFAR Antibody - AKR7A2 antibody detects AKR7A2 protein at cytosol on SkHep1 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded SkHep2 xenograft. AKR7A2 antibody dilution:1:500.
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal (aa84-359) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
AKR7A2 / AFAR Antibody - Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
AKR7A2 / AFAR Antibody - Immunohistochemistry of paraffin-embedded mouse heart using AKR7A2 antibodyat dilution of 1:100 (40x lens).
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
AKR7A2 / AFAR Antibody - Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
AKR7A2 / AFAR Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
AKR7A2 / AFAR Antibody - Western blot of anti-AKR7A2 antibody in 293 cell line lysates (35 ug/lane). AKR7A2 (arrow) was detected using the purified antibody. Western blot of anti-AKR7A2 Antibody in mouse liver tissue lysates (35 ug/lane). AKR7A2 (arrow) was detected using the purified antibody.
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal (aa101-129) Antibody
Mouse, Human
IHC, WB
Unconjugated
400 µl/$393
AKR7A2 / AFAR Antibody - Western blot of AKR7A2 pAb in extracts from HepG2 cells.
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
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AKR7A2 / AFAR Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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AKR7A2 / AFAR Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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AKR7A2 / AFAR Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
AKR7A2 / AFAR Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
AKR7A2 / AFAR Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
Select
AKR7A2 / AFAR Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
AKR7A2 / AFAR Antibody
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, WB
Unconjugated
100 µl/$332
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
AKR7A2 / AFAR Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
AKR7A2 / AFAR Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
AKR7A2 / AFAR Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
AKR7A2 / AFAR Antibody - AKR7A2 / AFAR antibody Western Blot of Human Liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal (aa82-131) Antibody
Human
WB
Unconjugated
100 µl/$424
AKR7A2 / AFAR Antibody - Western blot of ARK72 Antibody with human Fetal Lung lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AKR7A2 / AFAR Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
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AKR7A2 / AFAR Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-25 of 33 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).