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AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
| Gene Name: | aldo-keto reductase family 1, member B10 (aldose reductase) |
| Synonyms: | AKR1B10, AKR1B11, Aldose reductase-like peptide, ALDRLn, AKR1B12, Aldose reductase-like, Aldose reductase-like 1, ARP, HARP, HSI, Small intestine reductase, ARL-1, SI reductase |
| Target Sequences: | NM_020299 NP_064695.3 O60218 |
Publications (6)
1
Aldo-keto reductase family 1 B10 gene silencing results in growth inhibition of colorectal cancer cells: Implication for cancer intervention. Yan R, Zu X, Ma J, Liu Z, Adeyanju M, Cao D. International journal of cancer. Journal international du cancer. 2007 121:2301-6.
[PubMed:17597105]
2
Aldo-keto reductase family 1 B10 affects fatty acid synthesis by regulating the stability of acetyl-CoA carboxylase-alpha in breast cancer cells. Ma J, Yan R, Zu X, Cheng JM, Rao K, Liao DF, Cao D. The Journal of biological chemistry. 2008 283:3418-23.
[PubMed:18056116]
3
Oxidation of PAH trans-dihydrodiols by human aldo-keto reductase AKR1B10. Quinn AM, Harvey RG, Penning TM. Chemical research in toxicology. 2008 21:2207-15.
[PubMed:18788756]
[PMC:PMC2645959]
☰ Filters
Products
ELISA Kits
(4)
Type
Competitive EIA
(2)
Sandwich
(2)
Target
AKR1B10
(4)
Reactivity
Human
(4)
Format
96-Well Microplate
(1)
96-Well Strip Plate
(3)
Publications
No
(4)
Sample Type
Plasma
(4)
Serum
(4)
Tissue Homogenates
(2)
Sandwich
96-Well Microplate
Human
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Competitive EIA
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Competitive EIA
96-Well Strip Plate
Human
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$897
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