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AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
| Gene Name: | aldo-keto reductase family 1, member B10 (aldose reductase) |
| Synonyms: | AKR1B10, AKR1B11, Aldose reductase-like peptide, ALDRLn, AKR1B12, Aldose reductase-like, Aldose reductase-like 1, ARP, HARP, HSI, Small intestine reductase, ARL-1, SI reductase |
| Target Sequences: | NM_020299 NP_064695.3 O60218 |
Publications (6)
1
Aldo-keto reductase family 1 B10 gene silencing results in growth inhibition of colorectal cancer cells: Implication for cancer intervention. Yan R, Zu X, Ma J, Liu Z, Adeyanju M, Cao D. International journal of cancer. Journal international du cancer. 2007 121:2301-6.
[PubMed:17597105]
2
Aldo-keto reductase family 1 B10 affects fatty acid synthesis by regulating the stability of acetyl-CoA carboxylase-alpha in breast cancer cells. Ma J, Yan R, Zu X, Cheng JM, Rao K, Liao DF, Cao D. The Journal of biological chemistry. 2008 283:3418-23.
[PubMed:18056116]
3
Oxidation of PAH trans-dihydrodiols by human aldo-keto reductase AKR1B10. Quinn AM, Harvey RG, Penning TM. Chemical research in toxicology. 2008 21:2207-15.
[PubMed:18788756]
[PMC:PMC2645959]
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AKR1B10
(38)
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(31)
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(3)
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(2)
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(14)
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aa101-130
(7)
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(4)
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(2)
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(38)
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(4)
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(1)
AKR1B10 Mouse anti-Human Monoclonal (1A6) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
AKR1B10 Rabbit anti-Human Polyclonal (aa100-200) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
Sandwich
96-Well Microplate
Human
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
AKR1B10 Rabbit anti-Human Polyclonal (aa1-316) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
AKR1B10 Rabbit anti-Human Polyclonal (aa1-316) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µl/$460
AKR1B10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
E. coli
None
Biologically active
100 µg/$361; 500 µg/$739; 20 µg/$261
AKR1B10 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
200 µl/$952
AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
AKR1B10 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P, WB
Unconjugated
100 µg/$575
AKR1B10 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
AKR1B10 Goat anti-Human Polyclonal (aa303-315) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
AKR1B10 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
AKR1B10 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
AKR1B10 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
AKR1B10 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
AKR1B10 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
AKR1B10 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
AKR1B10 Rabbit anti-Human Polyclonal (aa51-100) Antibody
Human
WB
Unconjugated
100 µl/$397
AKR1B10 Rabbit anti-Human Polyclonal (aa101-130) Antibody
Human
WB
Unconjugated
400 µl/$393
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