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AKR1B1 / Aldose Reductase
aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B1 / Aldose Reductase is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.
| Gene Name: | aldo-keto reductase family 1, member B1 (aldose reductase) |
| Synonyms: | AKR1B1, Aldose reductase, ALDR1, ADR, Aldehyde reductase, Aldehyde reductase 1, ALR2, Lii5-2 CTCL tumor antigen, Low Km aldose reductase |
| Target Sequences: | NM_001628 NP_001619.1 P15121 |
Publications (2)
1
Effect of Tahiti lime (Citrus latifolia) juice on the Production of the PGF2a/PGE2 and Pro-Inflammatory Cytokines involved in Menstruation. Thaiane Robeldo , Edione Fatima Canzi, Priscila Maria de Andrade , Jhonne Pedro Pedotte Santana, Felipe Roberti Teixeira, Valentine Spagnol, Beatriz Helena Lameiro Noronha Sales Maia, Maristela Carbol, Erika Gonçalves Caneira, Maria Fátima das Graças Fernandes Da Silva, Ricardo Carneiro Borra. Scientific reports. 2020 Apr;10:7063. [Full Text Article]
[PubMed:32341436]
[PMC:PMC7184590]
2
Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation. Keshav Gopal, Qutuba G Karwi, Seyed Amirhossein Tabatabaei Dakhili, Cory S Wagg, Liyan Zhang, Qiuyu Sun, Christina T Saed, Sai Panidarapu, Riccardo Perfetti, Ravichandran Ramasamy, John R Ussher, Gary D Lopaschuk. Cardiovascular Diabetology. 2023 March;22:73. [Full Text Article]
[PubMed:36978133]
[PMC:PMC10045278]
Related Antibodies: LS-C331634.
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AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Dog, Guinea pig, Rat, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
AKR1B1 / Aldose Reductase Mouse anti-Human Monoclonal (2D12) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal (aa290-316) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal (aa241-290) Antibody
Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal (aa102-135) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal (210-290 aa, C-terminal) Antibody
Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal (Lys275) Antibody
Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µl/$412
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
AKR1B1 / Aldose Reductase Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
AKR1B1 / Aldose Reductase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$412
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