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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3.
Gene Name: | A kinase (PRKA) anchor protein 9 |
Synonyms: | AKAP9, A-kinase anchor protein 9, AKAP9-BRAF fusion protein, AKAP350, AKAP450, AKAP 350, AKAP 450, CG-NAP, AKAP 120-like protein, AKAP-9, HgAKAP 350, HYPERION, KIAA0803, Kinase N-associated protein, LQT11, PRKA9, MU-RMS-40.16A, Protein hyperion, Protein yotiao, YOTIAO, PPP1R45 |
Target Sequences: | NM_005751 NP_005742.4 Q99996 |
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