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Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.
Gene Name: | A kinase (PRKA) anchor protein 7 |
Synonyms: | AKAP7, A-kinase anchor protein 9 kDa, A-kinase anchor protein 18 kDa, AKAP-7 isoforms alpha and beta, AKAP-7 isoform gamma, AKAP 18, AKAP15, AKAP18, PRKA7 isoform gamma, PRKA7 isoforms alpha/beta |
Target Sequences: | NM_016377 NP_057461.2 Q9P0M2 |
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