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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.
Gene Name: | A kinase (PRKA) anchor protein 1 |
Synonyms: | AKAP1, AKAP, AKAP121, AKAP149, AKAP 149, AKAP84, D-AKAP1, S-AKAP84, SAKAP84, PRKA1, Protein kinase A1, D-AKAP-1, PPP1R43 |
Target Sequences: | NM_003488 NP_003479.1 Q92667 |
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