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AK1 / Adenylate Kinase 1

adenylate kinase 1

Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. AK1 is involved in the adenine nucleotide catabolic pathway, production of ADP, and in the homeostasis of guanine nucleotide pools. Adenylate kinase 1 phosphorylates AMP in red blood cells; deficiency in AK1 is the cause nonspherocytic hemolytic anemia. This small ubiquitous enzyme is essential for maintenance and cell growth. Three isozymes of adenylate kinase have been identified in vertebrates. AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. Alternative splicing of the AK1 gene yields two transcripts that differ in the 3-prime non-coding region and use two distinct polyadenylation signals.

Gene Name: adenylate kinase 1
Family/Subfamily: Non-protein Kinase , not assigned-Non-protein Kinase
Synonyms: AK1, Adenylate kinase isoenzyme 1, Adenylate kinase 1, AK 1, ATP-AMP transphosphorylase 1, Myokinase
Target Sequences: NM_000476 NP_000467.1 P00568

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Products
Antibodies (81)
Primary (81)
AK1 / Adenylate Kinase 1 (81)
Human (69)
Mouse (21)
Rat (16)
Bat (3)
Bovine (3)
Chicken (3)
Chimpanzee (6)
Dog (3)
Gibbon (3)
Guinea pig (3)
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Monkey (8)
Orangutan (3)
Pig (7)
Rabbit (6)
Sheep (3)
IHC (30)
IHC-P (8)
WB (70)
Flo (11)
ELISA (41)
ICC (3)
ID (2)
IE (2)
IF (30)
IP (8)
Peptide-ELISA (3)
rabbit (57)
mouse (21)
sheep (3)
Product Group
IHCPlus (2)
IgG (42)
IgG1 (10)
IgG1,k (9)
IgG2b (2)
monoclonal mc (21)
polyclonal pc (60)
1108CT2.4.1 (1)
3A6-1F5 (1)
3G8-1B11 (1)
AT7E9 (1)
OTI18C7 (2)
OTI19D1 (2)
OTI19G4 (2)
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Preservative Free (2)
Unconjugated (49)
aa165-194 (7)
aa30-59 (7)
aa1-194 (4)
aa108-157 (4)
aa36-85 (4)
70-150 aa, Internal (1)
C-Terminus (1)
aa1-195 (1)
aa101-150 (1)
No (81)
AK1 / Adenylate Kinase 1 Antibody - Immunohistochemistry of paraffin-embedded human esophageal cancer using AK1 antibodyat dilution of 1:100 (40x lens).
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AK1 / Adenylate Kinase 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
AK1 / Adenylate Kinase 1 Antibody - Anti-AK1 / Adenylate Kinase 1 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AK1 / Adenylate Kinase 1 Rabbit anti-Human Polyclonal (aa108-157) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
AK1 / Adenylate Kinase 1 Antibody - Immunofluorescent staining of HT29 cells using anti-AK1 mouse monoclonal antibody.
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AK1 / Adenylate Kinase 1 Mouse anti-Human Monoclonal (Carrier-free) (OTI5G8) Antibody
Human
IF, WB
Unconjugated, Carrier-free
100 µg/$511
AK1 / Adenylate Kinase 1 Antibody - Western blot of anti-AK1 antibody in Jurkat cell line lysate (35 ug/lane). AK1(arrow) was detected using the purified antibody.
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AK1 / Adenylate Kinase 1 Rabbit anti-Human Polyclonal (aa30-59) Antibody
Human
WB
Unconjugated
400 µl/$393
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AK1 / Adenylate Kinase 1 Rabbit anti-Pig Polyclonal Antibody
Pig
ELISA, IF, IHC, WB
Unconjugated
10 mg/$335
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AK1 / Adenylate Kinase 1 Rabbit anti-Pig Polyclonal (Biotin) Antibody
Pig
ELISA, IF, IHC, WB
Biotin Conjugated
1 ml/$438
AK1 / Adenylate Kinase 1 Antibody - Immunofluorescent staining of HT29 cells using anti-AK1 mouse monoclonal antibody.
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AK1 / Adenylate Kinase 1 Mouse anti-Human Monoclonal (OTI19D1) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated
100 µl/$434
AK1 / Adenylate Kinase 1 Antibody - Immunofluorescent staining of HT29 cells using anti-AK1 mouse monoclonal antibody.
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AK1 / Adenylate Kinase 1 Mouse anti-Human Monoclonal (Carrier-free) (OTI19D1) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
AK1 / Adenylate Kinase 1 Antibody - Anti-AK1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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AK1 / Adenylate Kinase 1 Rabbit anti-Human Polyclonal (aa101-150) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$460
AK1 / Adenylate Kinase 1 Antibody
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AK1 / Adenylate Kinase 1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
AK1 / Adenylate Kinase 1 Antibody - ICC/IF analysis of AK1 in HeLa cell line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human AK1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).ICC/IF analysis of AK1 in Hep3B cell line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human AK1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).ICC/IF analysis of AK1 in A549 cell line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human AK1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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AK1 / Adenylate Kinase 1 Mouse anti-Human Monoclonal (AT7E9) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
AK1 / Adenylate Kinase 1 Antibody - Immunohistochemistry of paraffin-embedded rat lung using AK1 Antibody at dilution of 1:100 (40x lens).
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AK1 / Adenylate Kinase 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
AK1 / Adenylate Kinase 1 Antibody - Anti-AK1 mouse monoclonal antibody  immunofluorescent staining of Hela cells transiently transfected by pCMV6-ENTRY AK1.
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AK1 / Adenylate Kinase 1 Mouse anti-Human Monoclonal (OTI18C7) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
AK1 / Adenylate Kinase 1 Antibody - Anti-AK1 mouse monoclonal antibody  immunofluorescent staining of Hela cells transiently transfected by pCMV6-ENTRY AK1.
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AK1 / Adenylate Kinase 1 Mouse anti-Human Monoclonal (Carrier-free) (OTI18C7) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
AK1 / Adenylate Kinase 1 Antibody - Anti-AK1 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY AK1.
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AK1 / Adenylate Kinase 1 Mouse anti-Human Monoclonal (OTI8A1) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated
100 µl/$434
AK1 / Adenylate Kinase 1 Antibody - Anti-AK1 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY AK1.
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AK1 / Adenylate Kinase 1 Mouse anti-Human Monoclonal (Carrier-free) (OTI8A1) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
AK1 / Adenylate Kinase 1 Antibody - Immunofluorescent staining of HT29 cells using anti-AK1 mouse monoclonal antibody.
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AK1 / Adenylate Kinase 1 Mouse anti-Human Monoclonal (OTI4A1) Antibody
Flo, IF, WB
Unconjugated
100 µl/$434
AK1 / Adenylate Kinase 1 Antibody - Immunofluorescent staining of HT29 cells using anti-AK1 mouse monoclonal antibody.
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AK1 / Adenylate Kinase 1 Mouse anti-Human Monoclonal (Carrier-free) (OTI4A1) Antibody
Human, Monkey
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
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AK1 / Adenylate Kinase 1 Mouse anti-Human Monoclonal (aa1-195) (3A6-1F5) Antibody
Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$705
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AK1 / Adenylate Kinase 1 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IF, IP, WB
APC Conjugated
100 µl/$904
AK1 / Adenylate Kinase 1 Antibody - Immunohistochemistry of paraffin-embedded human skeletal muscle tissue at dilution 1:100
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AK1 / Adenylate Kinase 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
AK1 / Adenylate Kinase 1 Antibody - 1:100 staining human skeletal muscle tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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AK1 / Adenylate Kinase 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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AK1 / Adenylate Kinase 1 Sheep anti-Rabbit Polyclonal Antibody
Rabbit
ELISA, IF, IHC, WB
Unconjugated
10 mg/$335
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AK1 / Adenylate Kinase 1 Sheep anti-Rabbit Polyclonal Antibody
Rabbit
ELISA, IF, IHC, WB
Unconjugated
1 mg/$520
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AK1 / Adenylate Kinase 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC
Unconjugated
50 µg/$305; 100 µg/$357
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).