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AIMP2

aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Gene Name: aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Synonyms: AIMP2, JTV1, JTV-1, PRO0992, Protein JTV-1, p38
Target Sequences: NM_006303 NP_006294.2 Q13155

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Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
AIMP2 (5)
No (5)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (2)
AIMP2 Protein - 12.5% SDS-PAGE of human JTV1 stained with Coomassie Blue
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Wheat Germ Extract
GST
61.7 kDa
2 µg/$439
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Wheat Germ Extract
GST, N-terminus
25 µg/$670; 10 µg/$479
AIMP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
35.2 kDa
20 µg/$150
AIMP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
35.2 kDa
100 µg/$494
AIMP2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Viewing 1-5 of 5 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).