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Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Gene Name: | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 |
Synonyms: | AIMP2, JTV1, JTV-1, PRO0992, Protein JTV-1, p38 |
Target Sequences: | NM_006303 NP_006294.2 Q13155 |
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