AIM2

absent in melanoma 2

Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (By similarity). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.

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Antibodies (57)

ELISA Kits (10)

Proteins (3)

Type

Custom (1)

Primary (57)

Recombinant (3)

Sandwich (8)

Sandwich CLIA (1)

Target

AIM2 (70)

Reactivity

Human (61)

Mouse (7)

Rat (1)

Chicken (1)

Gibbon (3)

Horse (3)

Monkey (4)

Pig (8)

Porcine (1)

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IHC (11)

IHC-P (4)

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ELISA (20)

ICC (7)

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IP (1)

Peptide-ELISA (6)

Host

rabbit (48)

mouse (6)

goat (3)

Product Group

IHCPlus (1)

Isotype

IgG (34)

IgG1 (2)

IgG2a,k (2)

IgM (1)

Clonality

monoclonal mc (5)

polyclonal pc (52)

Clone

3C4G11 (1)

7G12D1 (1)

812CT9.2.2.1 (1)

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IMG10M5G5 (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (8)

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Azide-free (1)

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aa1-343 (8)

aa4-32 (7)

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30-110 aa, Internal (1)

Ala78 (1)

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aa14-215 (1)

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No (70)

Sample Type

Cell Lysates (1)

Plasma (5)

Serum (6)

Tissue Homogenates (2)

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GST (2)

His, N-Terminal (1)

Species

Human (3)

Source

Baculovirus (1)

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Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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AIM2 Antibody (Internal) LS-C354127

Antibody:

AIM2 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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AIM2 Antibody (aa4-32) LS-C156196

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

400 µl/$393

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AIM2 Antibody (aa14-215) LS-C407895

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa14-215) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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AIM2 Antibody (N-Terminus) LS-C81558

Antibody:

AIM2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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AIM2 Antibody LS-C137251

Antibody:

AIM2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

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IHC-plus™ AIM2 Antibody (C-Terminus) LS-B5945

(4.0) Rating

Antibody:

AIM2 Goat anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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Human AIM2 (Sandwich ELISA) ELISA Kit - LS-F21269

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human AIM2 Protein (Recombinant His, N-Terminal) (aa1-343) - LS-G25710

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

43.7 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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AIM2 Antibody LS-C804624

Antibody:

AIM2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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AIM2 Antibody (aa93-342) LS-C178548

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa93-342) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$332

Select

AIM2 Antibody LS-C498354

Antibody:

AIM2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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AIM2 Antibody (aa4-32) LS-C319389

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, WB

Format:

Unconjugated

Price:

200 µl/$734

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AIM2 Antibody (aa4-32, Biotin) LS-C251075

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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AIM2 Antibody (aa4-32, FITC) LS-C251076

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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AIM2 Antibody (aa4-32, APC) LS-C251074

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

AIM2 Antibody (aa4-32, PE) LS-C251078

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

PE Conjugated

Price:

200 µl/$952

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AIM2 Antibody (aa4-32, Azide-free, HRP) LS-C251077

Antibody:

AIM2 Rabbit anti-Human Polyclonal (aa4-32) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, ICC, IF, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

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AIM2 Antibody (30-110 aa, Internal) LS-C381956

Antibody:

AIM2 Rabbit anti-Human Polyclonal (30-110 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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Mouse AIM2 (Sandwich ELISA) ELISA Kit - LS-F19344

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.25 - 80 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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AIM2 Antibody (clone 7G12D1) LS-C669398

Antibody:

AIM2 Mouse anti-Human Monoclonal (7G12D1) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µl/$459

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AIM2 Antibody LS-C659200

Antibody:

AIM2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

AIM2 Antibody (Internal) LS-C137125

Antibody:

AIM2 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µl/$332

Select

AIM2 Antibody LS-C815848

Antibody:

AIM2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

AIM2 Antibody (clone 3C4G11) LS-C669272

Antibody:

AIM2 Mouse anti-Human Monoclonal (3C4G11) Antibody

Reactivity:

Human

Applications:

ELISA, Flo

Format:

Unconjugated

Price:

100 µl/$459

Select

AIM2 Antibody (Ala78) LS-C192022

Antibody:

AIM2 Rabbit anti-Human Polyclonal (Ala78) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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