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AICAR / ATIC

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

AICAR / ATIC is a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.

Gene Name: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Synonyms: ATIC, AICAR, AICARFT, IMPCHASE, PURH
Target Sequences: NM_004044 NP_004035.2 P31939

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ELISA Kits (2)
Sandwich (1)
Sandwich CLIA (1)
AICAR / ATIC (2)
Human (2)
12 x 8-Well Microstrips (1)
96-Well Strip Plate (1)
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Plasma (2)
Serum (2)
AICAR / ATIC ELISA Kit
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Sandwich
96-Well Strip Plate
Human
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
AICAR / ATIC ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
7.81 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).