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AICAR / ATIC

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

AICAR / ATIC is a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.

Gene Name: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Synonyms: ATIC, AICAR, AICARFT, IMPCHASE, PURH
Target Sequences: NM_004044 NP_004035.2 P31939

☰ Filters
Antibodies (38)
Proteins (5)
ELISA Kits (2)
Over-Expression Lysate (3)
Primary (38)
Recombinant (2)
Sandwich (1)
Sandwich CLIA (1)
AICAR / ATIC (45)
Human (40)
Mouse (17)
Rat (12)
Bat (3)
Bovine (4)
Chimpanzee (6)
Dog (10)
Drosophila (5)
Frog (1)
Gibbon (6)
Guinea pig (6)
Hamster (6)
Horse (4)
Monkey (5)
Orangutan (6)
Pig (7)
Rabbit (9)
Xenopus (1)
Zebrafish (3)
IHC (10)
IHC-P (7)
WB (34)
Flo (2)
ELISA (6)
ICC (2)
IF (4)
IP (1)
Peptide-ELISA (1)
rabbit (26)
mouse (12)
Product Group
IHCPlus (1)
IgG (24)
IgG1 (9)
monoclonal mc (12)
polyclonal pc (26)
F38 P7 H9 (1)
OTI1D2 (2)
OTI2C10 (2)
OTI4A10 (2)
12 x 8-Well Microstrips (1)
96-Well Strip Plate (1)
APC Conjugated (1)
Biotin Conjugated (4)
Carrier-free (3)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (24)
aa151-200 (4)
aa379-428 (4)
aa310-580 (1)
aa375-425 (1)
aa50-100 (1)
No (45)
Plasma (2)
Serum (2)
6His, N-terminus (1)
GST (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
AICAR / ATIC ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
AICAR / ATIC ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
7.81 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
AICAR / ATIC Antibody - Immunohistochemistry of paraffin-embedded rat brain tissue.
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AICAR / ATIC Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
AICAR / ATIC Antibody - Anti-ATIC antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.
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AICAR / ATIC Mouse anti-Human Monoclonal (F38 P7 H9) Antibody
Xenopus, Drosophila, Pig, Horse, Rabbit, Dog, Bovine, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$460
AICAR / ATIC Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC.
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AICAR / ATIC Mouse anti-Human Monoclonal (OTI1D2) Antibody
Mouse, Dog, Rat, Human, Monkey
Flo, WB
Unconjugated
100 µl/$434
AICAR / ATIC Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC.
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AICAR / ATIC Mouse anti-Human Monoclonal (Carrier-free) (OTI1D2) Antibody
Mouse, Dog, Rat, Human, Monkey
Flo, WB
Unconjugated, Carrier-free
100 µg/$511
AICAR / ATIC Antibody - Detection of Human ATIC by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-ATIC antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
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AICAR / ATIC Rabbit anti-Human Polyclonal (aa50-100) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
AICAR / ATIC Antibody - Immunohistochemical analysis of ATIC staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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AICAR / ATIC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
AICAR / ATIC Antibody - IHC of paraffin-embedded Colon ca using ATIC antibody at 1:100 dilution.
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AICAR / ATIC Rabbit anti-Human Polyclonal (aa310-580) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
Select
HEK 293 Cells
6His, N-terminus
67 kDa
100 µg/$298
Select
AICAR / ATIC Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$331
AICAR / ATIC Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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AICAR / ATIC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
AICAR / ATIC Antibody - ATIC antibody ATIC(5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AICAR / ATIC Rabbit anti-Human Polyclonal (aa379-428) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
AICAR / ATIC Antibody - ATIC antibody ATIC(5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AICAR / ATIC Rabbit anti-Human Polyclonal (aa379-428) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
AICAR / ATIC Antibody - ATIC antibody ATIC(5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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AICAR / ATIC Rabbit anti-Human Polyclonal (aa379-428) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
AICAR / ATIC Antibody - ATIC antibody ATIC(5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
AICAR / ATIC Rabbit anti-Human Polyclonal (aa379-428) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
Select
AICAR / ATIC Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
AICAR / ATIC Antibody - Left and Center: IHC of normal colon tissue and colon carcinoma tissue using ATIC antibody (ATIC). Right: Western blot of ATIC antibody on HT29 cell lysate.
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AICAR / ATIC Mouse anti-Frog Monoclonal Antibody
Frog, Drosophila, Mouse, Rat, Human
IHC, WB
Unconjugated
200 µg/$466
AICAR / ATIC Antibody - Western blot detection of ATIC in various tissues and cell lysates using ATIC mouse mAb (1:1000 diluted). Predicted band size: 64KDa. Observed band size: 64KDa.
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AICAR / ATIC Mouse anti-Human Monoclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
AICAR / ATIC Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using ATIC Antibody at dilution of 1:100
Select
AICAR / ATIC Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
AICAR / ATIC Mouse anti-Human Monoclonal Antibody
Rabbit, Human
WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
AICAR / ATIC Antibody - Western blot detection of ATIC in various tissue and cell lysates using ATIC antibody (1:1000 diluted).
Select
AICAR / ATIC Mouse anti-Human Monoclonal Antibody
Rabbit, Human
WB
Unconjugated
50 µl/$356; 100 µl/$461
AICAR / ATIC Antibody - Western blot detection of ATIC in various tissues and cell lysates using ATIC mouse monoclonal antibody (1:1000 dilution). Predicted band size: 64KDa. Observed band size:64KDa.
Select
AICAR / ATIC Mouse anti-Human Monoclonal Antibody
Mouse, Human
WB
Unconjugated
100 µl/$391
AICAR / ATIC Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC.
Select
AICAR / ATIC Mouse anti-Human Monoclonal (OTI2C10) Antibody
Mouse, Dog, Rat, Human, Monkey
WB
Unconjugated
100 µl/$434
AICAR / ATIC Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC.
Select
AICAR / ATIC Mouse anti-Human Monoclonal (OTI4A10) Antibody
Dog, Human
WB
Unconjugated
100 µl/$434
Viewing 1-25 of 45 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).