AHRR / AhR Repressor

aryl-hydrocarbon receptor repressor

Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.

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Proteins (2)

Type

Recombinant (2)

Target

AHRR / AhR Repressor (2)

Publications

No (2)

Tag

GST, N-terminus (1)

Species

Human (2)

Source

E. coli (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human AHRR / AhR Repressor Protein (Recombinant GST, N-terminus) (aa617-715) - LS-G62957

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human AHRR / AhR Repressor Protein (Recombinant) (Met1-Pro182) - LS-G133610

Source:

E. coli

Tag:

None

Molecular Weight:

50.4kDa

Price:

10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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