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AHR
aryl hydrocarbon receptor
Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
| Gene Name: | aryl hydrocarbon receptor |
| Synonyms: | AHR, Ah receptor, AH-receptor, Aryl hydrocarbon receptor, BHLHe76, Aromatic hydrocarbon receptor |
| Target Sequences: | NM_001621 NP_001612.1 P35869 |
Publications (9)
1
Characterization of polyclonal antibodies to the Ah receptor prepared by immunization with a synthetic peptide hapten. Poland A, Glover E, Bradfield CA. Molecular pharmacology. 1991 39:20-6.
[PubMed:1846218]
2
Baculovirus expression of the Ah receptor and Ah receptor nuclear translocater. Evidence for additional dioxin responsive element-binding species and factors required for signaling. Chan WK, Chu R, Jain S, Reddy JK, Bradfield CA. The Journal of biological chemistry. 1994 269:26464-71.
[PubMed:7929368]
3
Possible involvement of aryl hydrocarbon receptor (AhR) in adult T-cell leukemia (ATL) leukemogenesis: constitutive activation of AhR in ATL. Hayashibara T, Yamada Y, Mori N, Harasawa H, Sugahara K, Miyanishi T, Kamihira S, Tomonaga M. Biochemical and biophysical research communications. 2003 300:128-34.
[PubMed:12480531]
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AHR Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
Fast Shipping
AHR Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
AHR Rabbit anti-Human Polyclonal (aa2-51) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
AHR Mouse anti-Human Monoclonal (3B9) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
AHR Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Guinea pig, Rat, Human
IHC, IHC-P
Unconjugated
0.1 ml/$460
AHR Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Guinea pig, Rat, Human
ICC, IHC, IHC-P, IP, WB
Biotin Conjugated
0.1 ml/$416
AHR Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Flo, IHC-P, WB
Unconjugated
100 µg/$575
AHR Rabbit anti-Human Polyclonal (pSer36) Antibody
Chicken, Zebrafish, Rat, Rabbit, Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$315
E. coli
His, N-Terminal
32.5 kDa
10 µg/$313; 50 µg/$642; 100 µg/$1,020; 200 µg/$1,214; 1 mg/$2,450; 500 µg/$1,952; 5 mg/$4,481; 2 mg/$2,642
Sandwich
96-Well Microplate
Human
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Wheat Germ Extract
GST, N-terminus
122.5 kDa
2 µg/$439
293T Cells
Myc-DDK (Flag)
96 kDa
20 µg/$150
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$1,041
AHR Rabbit anti-Human Polyclonal (10-90 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
AHR Rabbit anti-Human Polyclonal (p36) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
AHR Rabbit anti-Human Polyclonal (aa32-81) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
AHR Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
IP, WB
Unconjugated
100 µl/$576
AHR Rabbit anti-Human Polyclonal (aa555-582) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Mouse
0.391 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
AHR Mouse anti-Mouse Monoclonal (aa18-21) (RPT9) Antibody
Mouse, Rat, Human
IHC, IHC-Fr, IP, WB
Unconjugated
100 µl/$842
AHR Rabbit anti-Human Polyclonal (aa555-582) Antibody
Mouse, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
AHR Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
Fast Shipping
AHR Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
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