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6737 Mowry Ave
Newark, CA 94560
United States
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AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5
Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C15:0-C20:4 at the sn-1 position using C18:1-CoA as the acyl donor. Also acts on lysophosphatidylethanolamine using oleoyl-CoA, but not arachidonoyl-CoA, and lysophosphatidylinositol using arachidonoyl-CoA, but not oleoyl-CoA. Activity toward lysophosphatidylglycerol not detectable.
| Gene Name: | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| Synonyms: | AGPAT5, 1AGPAT5, 1-AGP acyltransferase 5, 1-AGPAT 5, LPAAT-epsilon, LPAATE, LPAAT-e |
| Target Sequences: | NM_018361 NP_060831.2 Q9NUQ2 |
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