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AGK

acylglycerol kinase

Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.

Gene Name: acylglycerol kinase
Family/Subfamily: Non-protein Kinase , Diacylglycerol kinase
Synonyms: AGK, Acylglycerol kinase, CATC5, HAGK, MTDPS10, Multi-substrate lipid kinase, MULK, HsMuLK
Target Sequences: NM_018238 NP_060708.1 Q53H12

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AGK ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$730
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).