AGER / RAGE

advanced glycosylation end product-specific receptor

Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides.

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Products

ELISA Kits (43)

Type

Competitive EIA (2)

Custom (4)

Development Kit (1)

Sandwich (32)

Sandwich CLIA (4)

Target

AGER / RAGE (43)

Reactivity

Human (12)

Mouse (11)

Rat (10)

Chicken (1)

Guinea pig (1)

Monkey (2)

Porcine (2)

Rabbit (2)

Sheep (1)

Product Group

DevKit DuoPlus (1)

Format

12 x 8-Well Microstrips (3)

96-Well Microplate (8)

96-Well Strip Plate (31)

Antibody Pair and Standard (1)

Publications

No (43)

Sample Type

Cell Culture Supernatants (15)

Cell Lysates (7)

Cell Supernatant (6)

Plasma (38)

Serum (38)

Tissue Homogenates (10)

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Monkey AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F40878

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$728

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Rat AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F521

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.411 - 300 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

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Sheep AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F40881

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

39.063 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$760

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Porcine AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F40879

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Mouse AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F6397

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$782

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Mouse AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F507

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

13.71 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$760

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Human AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F1027

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

63 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum

Price:

1 Plate/$534

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Human AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F476

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

2.058 - 500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

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Human AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F2701

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

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Mouse AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F2702

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

Select

Rat AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F2797

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

Select

Human AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F12468

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

6.25 - 400 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

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Human AGER / RAGE (CLIA) ELISA Kit - LS-F29289

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

15.625 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Mouse AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F34041

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F40255

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Rabbit AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F40880

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Guinea pig AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F40882

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Mouse AGER / RAGE (CLIA) ELISA Kit - LS-F30505

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Rat AGER / RAGE (CLIA) ELISA Kit - LS-F37664

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

12.5 - 800 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Mouse AGER / RAGE (Custom ELISA) ELISA Kit - LS-F56628

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$822

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DevKit DuoPlus Rat AGER / RAGE ELISA Development Kit - LS-F71938

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,254; 1000 Wells/$1,867

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Rat AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F56576

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F56355

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Porcine AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F75056

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$669

Select

Monkey AGER / RAGE (Sandwich ELISA) ELISA Kit - LS-F75020

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$669

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