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Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
Gene Name: | ATP/GTP binding protein-like 4 |
Synonyms: | AGBL4, ATP/GTP binding protein-like 4, ATP/GTP-binding protein-like 4, CCP6, Cytosolic carboxypeptidase 6 |
Target Sequences: | NM_032785 NP_116174.3 Q5VU57 |
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