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ADSL / Adenylosuccinate Lyase

adenylosuccinate lyase

Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: adenylosuccinate lyase
Synonyms: ADSL, Adenylosuccinate lyase, AMPS, ASASE, Adenylosuccinase
Target Sequences: NM_000026 NP_000017.1 P30566

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Antibodies (24)
Primary (24)
ADSL / Adenylosuccinate Lyase (24)
Human (23)
Mouse (6)
Rat (6)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (4)
IHC (6)
IHC-P (3)
WB (21)
Flo (3)
ELISA (6)
ICC (3)
IF (3)
IP (2)
rabbit (20)
mouse (4)
IgG (12)
IgG1 (2)
IgG1,k (1)
monoclonal mc (4)
polyclonal pc (20)
001 (1)
AT16C10 (1)
OTI2D10 (2)
APC Conjugated (1)
Biotin Conjugated (2)
Carrier-free (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (16)
aa188-237 (4)
aa1-310 (1)
aa200-250 (1)
aa202-441 (1)
No (24)
ADSL / Adenylosuccinate Lyase Antibody - Immunofluorescent analysis of ADSL staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
ADSL / Adenylosuccinate Lyase Antibody - Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-ADSL mouse monoclonal antibody.
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ADSL / Adenylosuccinate Lyase Mouse anti-Human Monoclonal (OTI2D10) Antibody
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ADSL / Adenylosuccinate Lyase Antibody - Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-ADSL mouse monoclonal antibody.
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ADSL / Adenylosuccinate Lyase Mouse anti-Human Monoclonal (Carrier-free) (OTI2D10) Antibody
Dog, Rat, Human, Monkey
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Monoclonal (Preservative Free) (001) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$412
ADSL / Adenylosuccinate Lyase Antibody - ICC/IF analysis of ADSL in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human ADSL antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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ADSL / Adenylosuccinate Lyase Mouse anti-Human Monoclonal (AT16C10) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
ADSL / Adenylosuccinate Lyase Antibody - Immunohistochemistry of paraffin-embedded human lung using antibody at 1:100 dilution.
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal (aa1-310) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
ADSL / Adenylosuccinate Lyase Antibody - Immunofluorescence analysis of HeLa cells.
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ADSL / Adenylosuccinate Lyase Antibody
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal (aa202-441) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$412
ADSL / Adenylosuccinate Lyase Antibody - Detection of human Adenylosuccinate Lyase/ADSL by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-Adenylosuccinate Lyase/ADSL antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal (aa200-250) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
ADSL / Adenylosuccinate Lyase Antibody - ADSL antibody Western blot of Fetal Muscle lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal (aa188-237) Antibody
Human
WB
Unconjugated
100 µl/$424
ADSL / Adenylosuccinate Lyase Antibody - ADSL antibody Western blot of Fetal Muscle lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal (aa188-237) (HRP) Antibody
Mouse, Dog, Guinea pig, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
ADSL / Adenylosuccinate Lyase Antibody - ADSL antibody Western blot of Fetal Muscle lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal (aa188-237) (Biotin) Antibody
Mouse, Dog, Guinea pig, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
ADSL / Adenylosuccinate Lyase Antibody - ADSL antibody Western blot of Fetal Muscle lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal (aa188-237) (FITC) Antibody
Mouse, Dog, Guinea pig, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
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ADSL / Adenylosuccinate Lyase Rabbit anti-Human Polyclonal Antibody
Human
Unconjugated
100 µg/$331
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ADSL / Adenylosuccinate Lyase Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-24 of 24 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).