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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

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ADRB1

adrenoceptor beta 1

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling.

Gene Name: adrenoceptor beta 1
Family/Subfamily: GPCR , Adrenergic
Synonyms: ADRB1, Adrenoceptor beta 1, Beta1-adrenergic receptor, Beta-1 adrenergic receptor, Beta1-adrenoceptor, B1AR, Beta-1 adrenoceptor, Beta-1 adrenoreceptor, BETA1AR, ADRB1R, Adrenergic, beta-1-, receptor, RHR
Target Sequences: NM_000684 NP_000675.1 P08588

Publications (2)

1
Distinct patterns of autoantibodies against G-protein-coupled receptors in Chagas' cardiomyopathy and megacolon. Their potential impact for early risk assessment in asymptomatic Chagas' patients. Wallukat G, Muoz Saravia SG, Haberland A, Bartel S, Araujo R, Valda G, Duchen D, Diaz Ramirez I, Borges AC, Schimke I. Journal of the American College of Cardiology. 2010 55:463-8. [PubMed:20117461] Related Antibodies: LS-C54455.
2
Aptamer neutralization of beta1-adrenoceptor autoantibodies isolated from patients with cardiomyopathies. Haberland A, Wallukat G, Dahmen C, Kage A, Schimke I. Circulation research. 2011 109:986-92. (IP) [PubMed:21868696] Related Antibodies: LS-C54455.

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ADRB1 Protein
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12.5 kD
100 µg/$570; 20 µg/$395; 1 mg/$1,973
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).