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ADRA2C

adrenoceptor alpha 2C

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.

Gene Name: adrenoceptor alpha 2C
Family/Subfamily: GPCR , Adrenergic
Synonyms: ADRA2C, ADRA2RL2, ADRARL2, Alpha-2C adrenergic receptor, Alpha-2c-2 adrenergic receptor, ADRA2L2, Adrenoceptor alpha 2C, Alpha-2C-adrenergic receptor, Alpha-2C-AR, Alpha-2CAR, Alpha-2C adrenoceptor, Alpha-2C adrenoreceptor, Alpha2c, ALPHA2CAR, Alpha 2c, Alpha2-AR-C4, Alpha2cii-adrenergic receptor
Target Sequences: NM_000683 NP_000674.2 P18825

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ELISA Kits (3)
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ADRA2C (3)
Human (2)
Mouse (1)
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96-Well Strip Plate (2)
No (3)
Adherent Cell Cultures (1)
Tissue Homogenates (2)
ADRA2C ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
ADRA2C ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$730
ADRA2C ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$783
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).