ADRA1B

adrenoceptor alpha 1B

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

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Proteins (2)

Type

Over-Expression Lysate (2)

Target

ADRA1B (2)

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No (2)

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Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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Human ADRA1B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74428

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.7 kDa

Price:

20 µg/$215

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ADRA1B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123040

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.7 kDa

Price:

100 µg/$710

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