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ADRA1B

adrenoceptor alpha 1B

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

Gene Name: adrenoceptor alpha 1B
Family/Subfamily: GPCR , Adrenergic
Synonyms: ADRA1B, Alpha 1b, Alpha-1B adrenergic receptor, Alpha-1b-adrenergic, Alpha-1B-adrenergic receptor, Alpha1b, Adrenoceptor alpha 1B, Alpha-1B adrenoreceptor, Alpha1B-AR, Alpha1beta-AR, ALPHA1BAR, ADRA1, Alpha-1B adrenoceptor, Alpha1b-adrenergic
Target Sequences: NM_000679 NP_000670.1 P35368

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Products
Antibodies (41)
Primary (41)
ADRA1B (41)
Human (41)
Mouse (15)
Rat (17)
Bat (3)
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Dog (8)
Gibbon (3)
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Rabbit (8)
IHC (14)
IHC-P (6)
WB (33)
Flo (1)
ELISA (20)
IF (4)
Peptide-ELISA (4)
rabbit (38)
mouse (1)
goat (2)
Product Group
GPCR Database Antibodies (4)
IHCPlus (3)
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IgG (22)
IgG2b (1)
monoclonal mc (1)
polyclonal pc (40)
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Azide-free (2)
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FITC Conjugated (4)
HRP Conjugated (4)
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Unconjugated (25)
aa270-297 (7)
aa380-409 (7)
aa169-218 (4)
aa388-437 (4)
C-Terminus (3)
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410-490 aa, C-terminal (1)
aa252-264 (1)
aa266-278 (1)
aa431-480 (1)
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No (41)
ADRA1B Antibody - Anti-ADRA1B antibody IHC of human smooth muscle cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ADRA1B Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
ADRA1B Antibody - Anti-ADRA1B antibody IHC of human adrenal, medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ADRA1B Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Bovine, Rat, Hamster, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
ADRA1B Antibody - Anti-ADRA1B antibody IHC of human kidney, collecting duct. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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ADRA1B Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
ADRA1B Antibody - Anti-ADRA1B antibody IHC of human smooth muscle cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ADRA1B Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
ADRA1B Antibody - Immunohistochemistry of paraffin-embedded Human colon cancer using ADRA1B Polyclonal Antibody at dilution of 1:20.
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ADRA1B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ADRA1B Antibody - Immunofluorescence analysis of LOVO cells, using ADRA1B Antibody. The picture on the right is blocked with the synthesized peptide.
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ADRA1B Rabbit anti-Human Polyclonal (aa431-480) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
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ADRA1B Mouse anti-Human Monoclonal Antibody
Human
Flo
Unconjugated
100 µg/$872
ADRA1B Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using ADRA1B Polyclonal Antibody at dilution of 1:25.
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ADRA1B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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ADRA1B Rabbit anti-Human Polyclonal (aa270-297) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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ADRA1B Rabbit anti-Human Polyclonal (aa270-297) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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ADRA1B Rabbit anti-Human Polyclonal (aa270-297) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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ADRA1B Rabbit anti-Human Polyclonal (aa270-297) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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ADRA1B Rabbit anti-Human Polyclonal (aa270-297) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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ADRA1B Rabbit anti-Human Polyclonal (aa270-297) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
ADRA1B Antibody - Western blot of AR-alpha1B antibody
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ADRA1B Rabbit anti-Human Polyclonal (410-490 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ADRA1B Antibody - Formalin-fixed and paraffin-embedded human brain with ADRA1B Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ADRA1B Rabbit anti-Human Polyclonal (aa270-297) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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ADRA1B Rabbit anti-Human Polyclonal (aa475-520) Antibody
Rat, Human
IF, WB
Unconjugated
50 µl/$321; 100 µl/$403
ADRA1B Antibody - Peptide - + Immunofluorescence analysis of LOVO cells, using ADRA1B antibody.
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ADRA1B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF
Unconjugated
100 µg/$357
ADRA1B Antibody - Western blot analysis of extracts of various cells.
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ADRA1B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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ADRA1B Rabbit anti-Human Polyclonal (aa380-409) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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ADRA1B Rabbit anti-Human Polyclonal (aa380-409) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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ADRA1B Rabbit anti-Human Polyclonal (aa380-409) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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ADRA1B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
ADRA1B Antibody
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ADRA1B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$332
ADRA1B Antibody - Western blot analysis of Adrenergic Receptor a-1B using COS7 whole cells lysates
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ADRA1B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).