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Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress.
Gene Name: | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
Family/Subfamily: | Protein Phosphatase , Protein Phosphatase - Provisional |
Synonyms: | ADPRM, ADPRibase-Mn, C17orf48, CDP-choline phosphohydrolase, MDS006, NBLA03831 |
Target Sequences: | NM_020233 NP_064618.3 Q3LIE5 |
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