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ADK / Adenosine Kinase

adenosine kinase

Adenosine kinase (ATP: adenosine 5-prime-phosphotransferase) is an abundant enzyme in mammalian tissues that catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of ADK could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as antiinflammatory agents. There are 2 ADK transcripts that encode a 345-amino acid form and a 362-amino acid form of the enzyme. These 2 alternately spliced forms differ only at the 5-prime end, where the first four encoded residues of the short form are replaced by 21 residues in the long form. When expressed, both isoforms of the enzyme phosphorylated adenosine with identical kinetics and both required Mg2+ for activity.

Gene Name: adenosine kinase
Synonyms: ADK, Adenosine 5-phosphotransferase, Adenosine kinase, AK
Target Sequences: NM_006721 NP_006712.2 P55263

☰ Filters
Antibodies (59)
Proteins (9)
ELISA Kits (5)
Custom (1)
Over-Expression Lysate (2)
Primary (59)
Recombinant (7)
Sandwich (4)
ADK / Adenosine Kinase (73)
Human (49)
Mouse (27)
Rat (9)
Penaeus monodon (4)
IHC (11)
IHC-P (7)
WB (49)
Flo (2)
ELISA (25)
ICC (2)
IF (4)
IP (1)
Peptide-ELISA (2)
rabbit (56)
mouse (3)
Product Group
IHCPlus (2)
IgG (32)
IgG1,k (2)
IgG2a,k (1)
monoclonal mc (4)
polyclonal pc (55)
001 (1)
1103CT3.4.3 (1)
4E7 (1)
AT4F8 (1)
96-Well Strip Plate (5)
APC (2)
APC Conjugated (4)
Azide-free (2)
Biotin Conjugated (7)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (4)
Preservative Free (2)
Unconjugated (26)
aa1-361 (8)
aa94-339 (8)
aa322-352 (7)
aa35-65 (7)
N-Terminus (6)
1-80 aa, N-terminal (1)
aa1-50 (1)
aa312-362 (1)
No (73)
Cell Lysates (2)
Plasma (2)
Serum (2)
Tissue Homogenates (2)
GST (1)
GST, N-terminus (1)
His (2)
His-GST (1)
His-GST-S (1)
Myc-DDK (Flag) (3)
Human (7)
Mouse (1)
293T Cells (1)
Baculovirus (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (1)
ADK / Adenosine Kinase Antibody - Anti-ADK antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ADK / Adenosine Kinase Mouse anti-Human Monoclonal (AT4F8) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
ADK / Adenosine Kinase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
ADK / Adenosine Kinase Antibody - Immunofluorescent analysis of Adenosine Kinase staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
100 µl/$299
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (1-80 aa, N-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ADK / Adenosine Kinase Antibody - ADK was detected in paraffin-embedded sections of mouse liver tissues using rabbit anti- ADK Antigen Affinity purified polyclonal antibody
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ADK / Adenosine Kinase Antibody - Western blot analysis of lysates from RAW264.7 and NIH/3T3 cells, using ADK Antibody. The lane on the right is blocked with the synthesized peptide.
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ADK / Adenosine Kinase Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE),a t a concentration of 5 ug/ml.
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (aa312-362) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
ADK / Adenosine Kinase Antibody - Immunohistochemistry image of paraffin-embedded human lung cancer at a dilution of 1:100
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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ADK / Adenosine Kinase Rabbit anti-Human Monoclonal (Preservative Free) (001) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (aa322-352) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (aa322-352) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (aa322-352) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (aa322-352) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (aa322-352) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (aa322-352) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
ADK / Adenosine Kinase Antibody - IHC testing of FFPE mouse liver with ADK antibody at 1ug/ml. HIER: steam sections in pH6 citrate buffer for 20 min.
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Flo, IHC-P, WB
Unconjugated
100 µg/$575
ADK / Adenosine Kinase Antibody - Staining RAW264.7 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ADK / Adenosine Kinase Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ADK antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (aa322-352) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
ADK / Adenosine Kinase Antibody - ADK Antibody (N-term) staining ADK in human kidney tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.
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ADK / Adenosine Kinase Mouse anti-Human Monoclonal (N-Terminus) (1103CT3.4.3) Antibody
Human
ELISA, IHC-P, WB
Unconjugated
200 µl/$393
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (aa35-65) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (aa35-65) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (aa35-65) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
ADK / Adenosine Kinase Antibody - Anti-ADK rabbit polyclonal antibody at 1:500 dilution. Lane A: RAW264.7 Whole Cell Lysate. Lane B: 293T Whole Cell Lysate. Lane C: NIH/3T3 Whole Cell Lysate. Lane D: Hela Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 40 kDa. Observed band size: 40 kDa. (We are unsure as to the identity of these extra bands.)
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ADK / Adenosine Kinase Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
100 µl/$412
ADK / Adenosine Kinase Antibody - Western blot analysis of extracts from RAW264.7 cells, using ADK antibody.
Select
ADK / Adenosine Kinase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
ADK / Adenosine Kinase Antibody - Western blot of ADK / Adenosine Kinase antibody.
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ADK / Adenosine Kinase Rabbit anti-Mouse Polyclonal (aa1-361) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
Viewing 1-25 of 73 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).