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ADGRL4 / ELTD1

EGF, latrophilin and seven transmembrane domain containing 1

The ETL protein receptor has been characterized as an Orphan-B GPCR with an unknown ligand. ETL has a large extracellular domain with epidermal growth factor (EGF)-like repeats, a seven-transmembrane domain, and a short cytoplasmic tail. ETL expression is developmentally regulated in heart.

Gene Name: EGF, latrophilin and seven transmembrane domain containing 1
Family/Subfamily: GPCR , Orphan-B
Synonyms: ADGRL4, ELTD1, ETL, ETL protein, KPG_003
Target Sequences: BC025721 AAH25721.1 Q9HBW9

Publications (2)

1
Adhesion G protein-coupled receptor, ELTD1, is a potential therapeutic target for retinoblastoma migration and invasion10<sup> Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, USA12<sup> Present address: AbbVie Bioresearch Center, Worcester, MA, USA14<sup> Department of Anatomy and Neurobiology, University of Puerto Rico, Medical Sciences Campus, PO Box 365067, San Juan, 00936-5067, Puerto Rico. jacqueline.flores@upr.edu. Jonathan Guihurt Santiago , Neikelyn Burgos-Tirado , Daniella Dorta Lafontaine , José C Mendoza Sierra , Roberto Herrera Camacho , Clara M Vecchini Rodríguez , Vanessa Morales-Tirado , Jacqueline Flores-Otero. BMC cancer. 2021 Jan;21:53. [Full Text Article] [PubMed:33430814] [PMC:PMC7802354] Related Antibodies: LS-C379622.
2
ELTD1 Promotes Gastric Cancer Cell Proliferation, Invasion and Epithelial-Mesenchymal Transition Through MAPK/ERK Signaling by Regulating CSK. Bo Sun, Fang-Jing Zhong. International journal of general medicine. 2021 Aug;14:4897-4911. [Full Text Article] [PubMed:34475781] [PMC:PMC8407680] Related Antibodies: LS-B15548.

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
ADGRL4 / ELTD1 (4)
No (4)
GST (2)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
ADGRL4 / ELTD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
77.6 kDa
20 µg/$150
ADGRL4 / ELTD1 Protein - 12.5% SDS-PAGE of human ELTD1 stained with Coomassie Blue
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Wheat Germ Extract
GST
95.1 kDa
10 µg/$479; 25 µg/$670
ADGRL4 / ELTD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
77.6 kDa
100 µg/$494
ADGRL4 / ELTD1 Protein
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GST
36.74kDa
10 µg/$479; 25 µg/$670
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).