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ADGRL3 / LPHN3
latrophilin 3
ADGRL3 / LPHN3 is a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane.
| Gene Name: | latrophilin 3 |
| Family/Subfamily: | GPCR , Orphan-B |
| Synonyms: | ADGRL3, CIRL3, CIRL-3, Lectomedin 3, Lectomedin-3, Lph3, KIAA0768, Latrophilin 3, Latrophilin homolog 3 (cow), LPHN3, Cl3 latrotoxin receptor, Latrophilin-3, LEC3 |
| Target Sequences: | NM_015236 NP_056051.2 Q9HAR2 |
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