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ADGRL1 / LPHN1

latrophilin 1

ADGRL1 / LPHN1 is a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.

Gene Name: latrophilin 1
Family/Subfamily: GPCR , Orphan-B
Synonyms: ADGRL1, Alpha-latrotoxin receptor, CIRL-1, CIRL1, Cl1 latrotoxin receptor, Latrophilin 1, Latrophilin-1, Lphh2, LPHN1, KIAA0821, LEC2, Cirl, CL1, Lectomedin-2
Target Sequences: NM_014921 NP_055736.2 O94910

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Products
Antibodies (23)
Primary (23)
ADGRL1 / LPHN1 (23)
Human (23)
Mouse (9)
Rat (9)
Bat (1)
Bovine (2)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Guinea pig (3)
Hamster (2)
Monkey (5)
Orangutan (3)
Pig (1)
Rabbit (1)
IHC (1)
IHC-P (2)
WB (18)
ELISA (8)
IF (3)
Peptide-ELISA (1)
rabbit (17)
mouse (6)
Product Group
GPCR Database Antibodies (2)
IHCPlus (1)
PathPlus Neuro (1)
IgG (9)
IgG2a,k (6)
monoclonal mc (6)
polyclonal pc (17)
APC Conjugated (2)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (10)
aa1252-1301 (4)
530-610 aa, Internal (1)
C-Terminus (1)
Internal (1)
N-Terminus (1)
aa561-610 (1)
No (23)
ADGRL1 / LPHN1 Antibody - Anti-LPHN1 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
ADGRL1 / LPHN1 Antibody - Western blot analysis of LPHN1 expression in HEK293T (A) whole cell lysates.
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Bovine, Rat, Human
WB
Unconjugated
100 µl/$299
ADGRL1 / LPHN1 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Hamster, Human, Monkey
IHC-P
Unconjugated
50 µg/$460
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (530-610 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ADGRL1 / LPHN1 Antibody - Western blot of LPHN1 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate.
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$391
ADGRL1 / LPHN1 Antibody - Peptide - + Immunofluorescence analysis of LOVO cells, using LPHN1 antibody.
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF
Unconjugated
100 µg/$357
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ADGRL1 / LPHN1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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ADGRL1 / LPHN1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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ADGRL1 / LPHN1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
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ADGRL1 / LPHN1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
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ADGRL1 / LPHN1 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
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ADGRL1 / LPHN1 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
ADGRL1 / LPHN1 Antibody - Immunofluorescence analysis of LOVO cells, using LPHN1 Antibody. The picture on the right is blocked with the synthesized peptide.
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (aa561-610) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
ADGRL1 / LPHN1 Antibody - LPHN1 / Latrophilin-1 antibody Western Blot of HeLa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (aa1252-1301) Antibody
Human
WB
Unconjugated
100 µl/$424
ADGRL1 / LPHN1 Antibody - LPHN1 / Latrophilin-1 antibody Western Blot of HeLa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (aa1252-1301) (HRP) Antibody
Mouse, Guinea pig, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
ADGRL1 / LPHN1 Antibody - LPHN1 / Latrophilin-1 antibody Western Blot of HeLa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (aa1252-1301) (Biotin) Antibody
Mouse, Guinea pig, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
ADGRL1 / LPHN1 Antibody - LPHN1 / Latrophilin-1 antibody Western Blot of HeLa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADGRL1 / LPHN1 Rabbit anti-Human Polyclonal (aa1252-1301) (FITC) Antibody
Mouse, Guinea pig, Rat, Chimpanzee, Orangutan, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
Viewing 1-23 of 23 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).