ADGRG1 / GPR56

G protein-coupled receptor 56

Involved in cell adhesion and probably in cell-cell interactions. Regulates the migration of neural precursor cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basemant membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Isoforms show differences in receptor signaling, specifically in serum response element (SRE) transcriptional activation upon overexpression. Overexpression inhibits melanoma tumor growth and metastasis and, during melanoma progression, regulates VEGFA production and angiogenesis through PRKCA; unprocessed GPR56 is inhibiting and GPR56 NT is activating angiogenesis. Required for normal cortical development and regulation of neuroprogenitor cells proliferation.

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Products

Proteins (12)

Type

Over-Expression Lysate (6)

Recombinant (6)

Target

ADGRG1 / GPR56 (12)

Publications

No (12)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (9)

Species

Human (9)

Source

293T Cells (3)

HEK 293 Cells (6)

Human Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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Human ADGRG1 / GPR56 Protein (Recombinant GST) (Full Length) - LS-G31568

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

104.1 kDa

Price:

2 µg/$439

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Human ADGRG1 / GPR56 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88146

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.75 kDa

Price:

20 µg/$215

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Human ADGRG1 / GPR56 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88147

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.75 kDa

Price:

20 µg/$150

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Human ADGRG1 / GPR56 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88148

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

74.3 kDa

Price:

20 µg/$215

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Human ADGRG1 / GPR56 Protein (Recombinant His) (Met1-Val342) - LS-G98594

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

37.4 kDa

Price:

100 µg/$721

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ADGRG1 / GPR56 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G103210

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

74.3 kDa

Price:

100 µg/$710

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Human ADGRG1 / GPR56 Protein (Recombinant GST, N-terminus) (aa31-130) - LS-G64561

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ADGRG1 / GPR56 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70844

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

75 kDa

Price:

20 µg/$1,107

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Human ADGRG1 / GPR56 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70846

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

74.3 kDa

Price:

20 µg/$1,107

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Human ADGRG1 / GPR56 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70847

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

75 kDa

Price:

20 µg/$1,107

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ADGRG1 / GPR56 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126820

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.75 kDa

Price:

100 µg/$710

Select

ADGRG1 / GPR56 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100618

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.75 kDa

Price:

100 µg/$494

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