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Tumor endothelial marker 5 is an Orphan-U GPCR with an unknown ligand. Tumor Endothelial Marker 5, like GPR125, has a leucine rich repeat (LRR), an immunoglobulin (Ig) domain, and a hormone-binding domain (HBD). The Ig domain shows similarities to motilin and titin, while the LRR domain shows similarities to LRIG1 and SLIT1-2.
Gene Name: | G protein-coupled receptor 124 |
Family/Subfamily: | GPCR , Orphan-U |
Synonyms: | ADGRA2, G protein-coupled receptor 124, G-protein coupled receptor 124, TEM5, GPR124, KIAA1531, Tumor endothelial marker 5 |
Target Sequences: | AY181242 NP_116166.9 Q96PE1 |
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