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ADCYAP1R1 / PAC1 Receptor

adenylate cyclase activating polypeptide 1 (pituitary) receptor type I

The PACAP receptor type 1, a member of the vasoactive intestinal polypeptide subfamily, binds the hormone pituitary adenylate cyclase activating polypeptide (PACAP) with high affinity. PACAP is involved in stimulating the secretion of insulin, catecholamines, ACTH, and growth hormone. Additionally, PACAP appears to function as a neuromodulator/neurotransmitter in the central and peripheral nervous systems. Two start codons are reported in literature, one (nt 74-76) results in a 525-amino acid protein with a signal peptide of 77 amino acids encoded by nt 74-304 and the second (nt 245-247) initiates a 468-amino acid protein with a signal peptide of 20-amino acids encoded by nt 245-304. The efficiency of these two start codons is not known.

Gene Name: adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
Family/Subfamily: GPCR , Vasoactive intestinal polypeptide
Synonyms: ADCYAP1R1, PAC1, Pac1 receptor, Pac1 receptors, PAC1-R, PACAP receptor 1, Pacap specific receptor, PACAP-R-1, PACAP/VIP receptors, PACAP1 receptor, PACAP Receptor, Pacap receptor type 1, Pacap type 1 receptor, PACAP type I receptor, PACAPR, PAC1R, PACAP-R1, PACAPRI, Pvr1, Pacap receptor type i
Target Sequences: NM_001118 NP_001109.2 P41586

Publications (1)

1
The Potential of Asiatic Acid in the Reversion of Cyclophosphamide-Induced Hemorrhagic Cystitis in Rats. Andrzej Wróbel, Lukasz Zapala, Tomasz Kluz, Artur Rogowski, Marcin Misiek, Kajetan Juszczak, Jacek Sienko, Daniela Gold, Klaudia Stangel-Wójcikiewicz, Ewa Poleszak, Piotr Radziszewski. International journal of molecular sciences. 2021 May;22: [Full Text Article] [PubMed:34072606] [PMC:PMC8198845]

☰ Filters
Antibodies (26)
ELISA Kits (6)
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Primary (26)
Recombinant (3)
Sandwich (3)
ADCYAP1R1 / PAC1 Receptor (35)
Human (28)
Mouse (10)
Rat (11)
Bat (4)
Bovine (7)
Chicken (4)
Chimpanzee (3)
Dog (7)
Gibbon (6)
Guinea pig (6)
Horse (6)
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Rabbit (3)
Sheep (3)
Xenopus (4)
Zebrafish (3)
IHC (9)
IHC-P (5)
WB (21)
ELISA (11)
ICC (1)
IF (1)
Peptide-ELISA (1)
SDS-PAGE (1)
rabbit (19)
mouse (7)
Product Group
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IgG1,k (7)
monoclonal mc (7)
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aa325-374 (4)
aa343-392 (4)
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aa21-120 (1)
No (34)
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Human Cells (1)
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Low endotoxin level (2)
ADCYAP1R1 / PAC1 Receptor Antibody - Anti-ADCYAP1R1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
ADCYAP1R1 / PAC1 Receptor Antibody - Anti-ADCYAP1R1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Bovine, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
ADCYAP1R1 / PAC1 Receptor Antibody - Anti-ADCYAP1R1 / PAC1 Receptor antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Xenopus, Chicken, Bat, Dog, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
ADCYAP1R1 / PAC1 Receptor Antibody - Anti-ADCYAP1R1 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
ADCYAP1R1 / PAC1 Receptor Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (aa21-120) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$485
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ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
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ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
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ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
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ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
ADCYAP1R1 / PAC1 Receptor Antibody - 1:100 staining mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ADCYAP1R1 / PAC1 Receptor ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
ADCYAP1R1 / PAC1 Receptor Antibody - Immunohistochemistry of paraffin-embedded human tonsil tissue using ADCYAP1R1 antibody.
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ADCYAP1R1 / PAC1 Receptor Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (Extracellular) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$468
ADCYAP1R1 / PAC1 Receptor Antibody - ADCYAP1R1 monoclonal antibody (M01), clone 2B12 Western Blot analysis of ADCYAP1R1 expression in HeLa.
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ADCYAP1R1 / PAC1 Receptor Mouse anti-Human Monoclonal (2B12) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
ADCYAP1R1 / PAC1 Receptor Protein
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HEK 293 Cells
Human IgG Fc, C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human ADCYAP1R1/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 373 amino acids and has a predicted molecular mass of 42 kDa. The reduced monomer migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions due to glycosylation.
50 µg/$441
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
ADCYAP1R1 / PAC1 Receptor Antibody - Immunofluorescence staining of ADCYAP1R1 in SHSY5Y cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human ADCYAP1R1 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to Cytoplasm.
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
ADCYAP1R1 / PAC1 Receptor Antibody - ADCYAP1R1 antibody Western blot of Fetal Brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (aa343-392) Antibody
Human
WB
Unconjugated
100 µl/$424
ADCYAP1R1 / PAC1 Receptor Antibody - ADCYAP1R1 antibody Western blot of Fetal Brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (aa343-392) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
HRP Conjugated
100 µl/$469
ADCYAP1R1 / PAC1 Receptor Antibody - ADCYAP1R1 antibody Western blot of Fetal Brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (aa343-392) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
ADCYAP1R1 / PAC1 Receptor Antibody - ADCYAP1R1 antibody Western blot of Fetal Brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ADCYAP1R1 / PAC1 Receptor Rabbit anti-Human Polyclonal (aa343-392) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Rat, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
FITC Conjugated
100 µl/$469
Viewing 1-25 of 35 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).